Publications by authors named "Rodrigo R Provenza"
Background: Sperm deoxyribonucleic acid (DNA) fragmentation is commonly encountered in spermatozoa, and the oocyte assumes responsibility for repairing sperm DNA fragmentation during the oocyte-embryo transition.
Objectives: This study aimed to investigate whether the effect of sperm DNA fragmentation on intracytoplasmic sperm injection outcomes depends on the incidence of oocyte dimorphisms.
Materials And Methods: For the present cohort, 2942 fertilized oocytes from 525 patients submitted to intracytoplasmic sperm injection cycles were assessed.
Article Synopsis
- - This study investigated how sperm DNA fragmentation (SDF) affects the success of assisted reproductive technology in women of various ages, focusing on clinical outcomes like implantation and pregnancy rates.
- - It analyzed data from 540 couples undergoing intracytoplasmic sperm injection, dividing them into age groups and comparing results based on low (<30% SDF) and high (≥30% SDF) fragmentation indexes.
- - Results showed that older women (over 40) with higher SDF had significantly poorer embryo quality and lower pregnancy rates, while younger women had similar outcomes regardless of SDF levels.
Sperm DNA fragmentation is correlated with poor embryo development, lower implantation rate, and higher miscarriage rate in reproductive cycles of non-male factor infertility.
Fertil Steril
September 2019
Objective: To study the implications of sperm DNA fragmentation (SDF) in intracytoplasmic sperm injection cycles for non-male factor infertility.
Design: Prospective cohort study.
Setting: Private university-affiliated IVF center.
This prospective-cohort study aimed at investigating the influence of paternal lifestyle factors on semen parameters and intracytoplasmic sperm injection (ICSI) outcomes. The influence of paternal lifestyle factors on seminal quality and ICSI outcomes was investigated in male patients undergoing conventional semen analysis. Cigarette smoking negatively influenced semen volume (B: -0.
View Article and Find Full Text PDFObjective: To discuss the requirement from the National Health Surveillance Agency (ANVISA), for assisted reproduction treatment patients to undergo laboratory tests for ZIKV detection, and if the public health authorities and government leaders' recommendations to women simply avoid pregnancy is prudent.
Methods: This study was performed in a university-affiliated in vitro fertilization center in Brazil. We present a critical discussion on the risk of microcephaly due to ZIKV infection and the prevalence of other harmful pathogens to vulnerable pregnant women and infants.