Publications by authors named "Rodrigo P Lima"

Background/objective: The aim was to evaluate the use of bacterial cellulose film and bile duct autograft in repairing critical common bile duct injury in pigs.

Methods: A prospective experimental analytical study was carried out on 20 Sus Domesticus, Piau suidae swine, divided into a control group ( = 10) and an experimental group ( = 10) divided into two subgroups: bacterial cellulose film E1 and bacterial cellulose film E2 to which bacterial cellulose film was randomly allocated. The control group underwent two complete critical common bile duct sections 10 mm apart, while the experimental group with a single critical common bile duct defect underwent a 10 mm section of the longitudinal shaft with edge resection.

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The aim of this study is to evaluate if a gel of bacterial cellulose gel can revert the loss of anal resting pressure after anorectum sphincter injury in rat model, elected as a model to simulate fecal incontinence. Thirty-nine animals were equally divided into three groups: Control (CG), Sphincter injury plus Saline injection (SG) and Sphincter injury plus Bacterial Cellulose Gel injection (BCG). Anal pressure at rest was assessed for all animal in the three groups using anorectum manometry.

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Purpose: To evaluate the effects of particulate (granule-shaped) SCB on bone repair relating it to its biocompatibility and bone neoformation.

Methods: Thirty Wistar rats were submitted to a one 7-mm-diameter defect and divided equally into three experimental groups, with two different postoperative times of evaluation, 90 and 120 days. Each calvaria defect was filled up with clot (control group), particulated autogenous bone or granulated SCB.

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In higher eukaryotes, eIF4A, eIF4E and eIF4G homologues interact to enable mRNA recruitment to the ribosome. eIF4G acts as a scaffold for these interactions and also interacts with other proteins of the translational machinery. Trypanosomatid protozoa have multiple homologues of eIF4E and eIF4G and the precise function of each remains unclear.

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Special localized wave modes show up in several physical scenarios including BEC in optical lattices, nonlinear photonic crystals, and systems with strong electron-phonon interaction. These result from an underlying nonlinear contribution to the wave equation that is usually assumed to be instantaneous. Here we demonstrate that the relaxation process of the nonlinearity has a profound impact in the wave-packet dynamics and in the formation of localized modes.

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Article Synopsis
  • Translation initiation in eukaryotes relies on the eIF4E protein, which works with eIF4G in the eIF4F complex, and in Trypanosoma brucei, four homologues of eIF4E have been studied for their specific functions.
  • The homologues are divided into two groups based on their sequence: TbEIF4E1 and 2 resemble metazoan eIF4E1, while TbEIF4E3 and 4 have extended N-terminal regions and show strictly cytoplasmic localization.
  • Knockdown studies revealed that TbEIF4E3 is essential for the viability of the insect form, whereas TbEIF4E1, 3, and 4 are
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