Publications by authors named "Rodrigo L Sanz Duro"

We detected an emerging human-associated gemykibivirus-2 (HuGkV-2) in rectal swab sample from Molossus molossus bat from Brazil. Phylogenetic analysis further revealed well-supported relationships between our sequence and those associated with human infections. This study underscores the necessity of ongoing monitoring of HuGkV-2 to elucidate potential spillback events, its role in human infections, and its public health implications.

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Circular single stranded DNA viruses (CRESS DNA) encoding a homologous replication-associated protein (REP) have been identified in most of eukaryotic groups. It is not clear yet the role in human diseases or details of the life cycle of these viruses. Recently, much interest has been raised in the evolutionary history of CRESS DNA owing to the increasing number of new sequences obtained by Next-Generation Sequencing (NGS) in distinct host species.

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During 2006-2011, 5035 fecal samples were tested by PCR for human adenovirus (HAdV) and sequenced. HAdV was detected in 198 cases (3.9%), with the highest rate in children ≤ 5 years.

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Article Synopsis
  • The study investigated cases of coinfection with Chikungunya, Dengue, and Zika viruses in Tocantins, Brazil.
  • In 2017, 102 patient samples showing symptoms of arboviral infections were analyzed, confirming various infections using RT-qPCR.
  • Results showed 52 cases of Chikungunya only, multiple Dengue serotypes, and five instances of coinfection with Chikungunya and Dengue serotype 2, highlighting the need for better diagnosis and vector management.
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We investigated an outbreak of exanthematous illness in Maceió by using molecular surveillance; 76% of samples tested positive for chikungunya virus. Genetic analysis of 23 newly generated genomes identified the East/Central/South African genotype, suggesting that this lineage has persisted since mid-2014 in Brazil and may spread in the Americas and beyond.

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