Molecular characteristics of atopic dermatitis patients with clinical remission.

Introduction: Atopic dermatitis (AD) is a frequent disease in infants with diverse clinical evolution. Although multiple studies have assessed inflammatory changes in chronic AD, little is known about the molecular transition from symptomatic stage to clinical remission without pharmacotherapy.

Objective: The aim of the study was to evaluate clinical and inflammatory factors and its relationship with AD clinical evolution.

[IgE sensitization and sociodemographic conditions as determinant factors in asthma severity].

Background: In Latin America there are few data about the factors that influence the control and severity of asthma.

Objective: To describe the association between IgE sensitization to intra-home allergens and housing conditions in the severity of asthma.

Methods: Sensitization to aero-allergens was evaluated by skin prick test and socio-demographic data by a questionnaire in a population between 6 and 14 years of age with diagnosis of asthma.

[Prevalence of asthma in Latin America. Critical look at ISAAC and other studies].

Currently, the ISAAC (International Study of Asthma and Allergies in Childhood) project is a global approach to assess the prevalence of asthma and other allergies in different latitudes. One of the great advantages of this project is that it compares using the same methodology, the prevalence of asthma in more than 50 cities during the same period of time, nevertheless the reproducibility of these results when compared with other studies of prevalence in each region has not been evaluated. In this review we aim to compare the epidemiological data provided by the ISAAC against the data identified in some regional cohort studies and by means of a critical evaluation to highlight the main similarities and to analyze the differences between these epidemiological data.