Association between KRAS mutation and alcohol consumption in Brazilian patients with colorectal cancer.

Colorectal cancer (CRC) is a leading cause of morbidity and mortality worldwide. Detection before metastasis and efficient treatment of disease significantly improve patient survival and quality of life. However, limitations in diagnosis and postoperative surveillance are associated with low CRC detection and survival rates.

Agrometeorological and Agronomic Characterization of Grasses Cultivated in Tropical Humid and Semi-Arid Conditions: A Multivariate Approach.

Variability in climatic conditions of low-latitude tropical grass cultivation can affect forage production dynamics. Pasture ecosystems are complex and preferably studied from a multifactorial point of view through multivariate approaches. Therefore, in this study, we characterized different growing conditions for grasses of the genus through studies conducted in tropical humid and semi-arid conditions.

Microclimate and animal thermal comfort indexes in different silvopastoral system arrangements in Caatinga.

The objective was to evaluate the microclimate and animal thermal comfort indexes in silvopastoral system in the Brazilian semiarid region with different woody cover levels within Caatinga trees. The experiment was carried out at the Teaching, Research and Extension Unit of the Federal Institute of Science and Technology of Ceará, Campus Limoeiro do Norte, in Chapada do Apodi, CE, in 2018. The treatments were forage grown under woody cover of 46.

Hypertriglyceridemic waist phenotype and associated factors in individuals with arterial hypertension and/or diabetes mellitus.

Cardiovascular diseases are among the main causes of death in Brazil and worldwide. The literature indicates the hypertriglyceridemic waist phenotype (HTWP) as an accessible alternative for the identification of cardiovascular and metabolic risk. The present study aimed to identify the prevalence and factors associated with HTWP in individuals diagnosed with arterial hypertension (AH) and/or diabetes mellitus type 2 (DM2).

Low-grade albuminuria in adult and elderly individuals with diabetes mellitus and arterial hypertension accompanied by Primary Health Care.

Diabetes mellitus (DM) and arterial hypertension (AH) are the two main clinical conditions related to Chronic Kidney Disease (CKD); disease also identify by the levels of low-grade albuminuria (LGA). Few studies have simultaneously investigated the associations of glycated hemoglobin (HbA1c) and fasting plasma glucose (FPG) with LGA. Our study aimed to investigate and compare the association of HbA1c and FPG with the probability of LGA in adult and elderly individuals with DM and AH, within the scope of Primary Health Care (PHC).

Surgical results and quality of life of patients submitted to restorative proctocolectomy and ileal pouch-anal anastomosis.

Purpose: restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the surgical procedure of choice in some cases of familial adenomatous polyposis (FAP) and ulcerative colitis (UC). IPAA allows complete removal of the diseased colon and rectum, however, it is associated with substantial morbidity and potential consequences to patients' quality of life (QoL).

Aims: to evaluate the surgical results, functional outcomes and QoL after IPAA; and to examine the impact of surgical complications upon QoL.

Prevalence of chronic kidney disease in Brazilians with arterial hypertension and/or diabetes mellitus.

The present study aimed to evaluate the prevalence of chronic kidney disease (CKD) in individuals with arterial hypertension (AH) and/or diabetes mellitus (DM) accompanied by Primary Health Care (PHC) in Brazil. The estimated glomerular filtration rate (eGFR) based on creatinine, and urinary albumin-to-creatinine ratio (ACR) were measured in 841 subjects with AH and/or DM, followed by PHC in the city of Viçosa. The CKD was diagnosed according to KDIGO criteria.

Survival and analysis of predictors of mortality in patients undergoing replacement renal therapy: a 20-year cohort.

Background: optimal management of end-stage renal disease (ESRD) in hemodialysis (HD) patients should be more studied because it is a serious risk factor for mortality, being considered an unquestionable global priority.

Methods: we performed a retrospective cohort study from the Nephrology Service in Brazil evaluating the survival of patients with ESRD in HD during 20 years. Kaplan-Meier method with the Log-Rank and Cox's proportional hazards model explored the association between survival time and demographic factors, quality of treatment and laboratory values.

Individual and Combined Components of Metabolic Syndrome with Chronic Kidney Disease in Individuals with Hypertension and/or Diabetes Mellitus Accompanied by Primary Health Care.

Purpose: To identify the associations between MetS and its components and chronic kidney disease (CKD) in a population with arterial hypertension (AH), or diabetes mellitus (DM) accompanied by the Primary Health Care (PHC).

Patients And Methods: A cross-sectional study with 788 individuals diagnosed with AH and/or DM followed by PHC of Viçosa, Brazil. Anthropometric, biochemical and clinical measures were performed for the diagnosis of MetS and CKD.

Factors preventing restoration of bowel continuity in patients with rectal cancer submitted to anterior rectal resection and protective ileostomy.

Objective: to evaluate the factors associated with non-closure of protective ileostomy after anterior resection of the rectum with total mesorectum excision for rectal cancer, the morbidity associated with the closure of ileostomies and the rate of permanent ileostomy in patients with rectal adenocarcinoma.

Methods: we conducted a retrospective study with 174 consecutive patients diagnosed with rectal tumors, of whom 92 underwent anterior resection of the rectum with coloanal or colorectal anastomosis and protective ileostomy, with curative intent. We carried out a multivariate analysis to determine the factors associated with definite permanence of the stoma, as well as studied the morbidity of patients who underwent bowel continuity restoration.

Montreal classification of patient operated for Crohn's disease and identification of surgical recurrence predictors.

Objective: to evaluate Crohn's disease recurrence and its possible predictors in patients undergoing surgical treatment.

Methods: We conducted a retrospective study with Crohn's disease (CD) patients undergoing surgical treatment between January 1992 and January 2012, and regularly monitored at the Bowel Clinic of the Hospital das Clínicas of the UFMG.

Results: we evaluated 125 patients, 50.

Randomized Clinical Trial: Impact of Oral Administration of Saccharomyces boulardii on Gene Expression of Intestinal Cytokines in Patients Undergoing Colon Resection.

Background: When intestinal microbiota is imbalanced, a patient becomes more vulnerable to infectious complications; intervention with beneficial probiotics may help lower risk for infection. The aim of this study was to measure levels of inflammatory cytokine messenger RNA (mRNA) in surgical samples of intestinal mucosal tissues from patients who were given the probiotic Saccharomyces boulardii before undergoing colon surgery.

Methods: Thirty-three patients undergoing colon resection were randomly assigned to receive at least 7-day preoperative probiotic treatment (n = 15) or conventional (n = 18) treatment.

Male sexual function after total mesorectal excision: a comparison between laparoscopic and open surgery during the learning curve period.

Introduction: This study assessed male sexual function using a specific and validated questionnaire, the International Index of Erectile Function (IIEF), in patients subjected to open total mesorectal excision (OTME) and laparoscopic total mesorectal excision (LTME) and compared it with a control group.

Patients And Methods: The inclusion criteria consisted of male patients with an active sexual life before surgery subjected to OTME or LTME at the Coloproctological Unit of the Clinics Hospital, Minas Gerais Federal University, between January 2005 and September 2009. The IIEF questionnaire was used.

Colorectal carcinoma in different age groups : a histopathological analysis.

Purpose: Although colorectal cancer is typical in the older population, tumor onset before age 40 is not infrequent. However, the behavior, characteristics, and prognosis of this disease in young patients are unclear when compared to the older population. It is believed that young patients have a poor prognosis.

[Restoration of intestinal continuity after Hartmann's procedure].

Objective: To study was to investigate the associated morbidity and mortality of the restoration of intestinal continuity after Hartmann's procedure.

Methods: Hospital records of 29 patients undergoing surgery to restoration of intestinal continuity after Hartmann's procedure at Hospital das Clínicas da Universidade Federal de Minas Gerais between January 1998 and December 2006 were retrospectively analyzed. Demographic, morbidity and mortality data were colleted.

Effect of spleen surgeries on Escherichia coli distribution on the mononuclear phagocytic system.

Objective: To avoid asplenic state, many approaches preserving the spleen have been proposed in the literature: splenorraphy, partial splenectomy with or without preservation of hilar vessels and splenic tissue auto-implants. Subtotal splenectomy, preserving the upper spleen pole nourished only by splenogastric vessels is an alternative when the splenic pedicle must be ligated. The purpose of this study was to evaluate the influence of partial, subtotal and total splenectomies on the distribution of Escherichia coli in the mononuclear phagocytic system.

Late follow-up of patients submitted to subtotal splenectomy.

Background: Over the past 21years, we have performed more than 200 subtotal splenectomies, in which the upper splenic pole vascularized only by the gastrosplenic pole vascularized only by the gastrosplenic vessels is preserved, to treat different pathologic conditions. A meticulous follow-up of the postoperative results of this procedure is of fundamental importance.

Methods: All patients undergoing subtotal splenectomy were invited to be reviewed.

Analysis of prognostic factors in seventy patients having a complete cytoreduction plus perioperative intraperitoneal chemotherapy for carcinomatosis from colorectal cancer.

Background: Although lymph node and liver metastases are recognized as indications for resection of metastatic disease from colorectal cancer, carcinomatosis has not traditionally been regarded as having surgical treatment options. Reports have suggested that complete surgical removal of carcinomatosis combined with thorough irrigation of the peritoneal cavity with chemotherapy could result in longterm survival in selected patients. Proper selection factors are important because palliative surgery in these patients has not proved beneficial.

The impact of early nutrition on metabolic response and postoperative ileus.

Purpose Of Review: Early nutrition has been evaluated and used as a possible strategy to decrease the negative impact of the metabolic response to injury and postoperative ileus. The metabolic response to injury, be it surgical or traumatic, is a physiological mechanism that, according to the magnitude and duration of the event, can impact on the patient's morbidity and survival. The adequate initial approach is a determinant factor that might influence its outcome.