Eyeball Preservation With Purse-String Conjunctival Closure for Melting Corneal Ulcer in Rare Facial Cleft.

Rare facial clefts are characterized by facial involvement that is not restricted to the lip, palate, and alveolus as in traditional cleft lip and palate. The craniofacial skeleton and the orbital structures are frequently affected in these conditions. Exposure of the eyeball, when not early treated, puts the function and the preservation of the eye at risk.

Quenching Effects of Graphene Oxides on the Fluorescence Emission and Reactive Oxygen Species Generation of Chloroaluminum Phthalocyanine.

The photophysical behavior and reactive oxygen species (ROS) generation by chloroaluminum phthalocyanine (AlClPc) are evaluated by steady state absorption/emission, transient emission, and electron paramagnetic resonance spectroscopies in the presence of graphene oxide (GO), reduced graphene oxide (RGO), and carboxylated nanographene oxide (NGO). AlClPc and graphene oxides form a supramolecular structure stabilized by π-π interactions, which quantitatively quenches fluorescence emission and suppresses ROS generation. These effects occur even when graphenes are previously functionalized with Pluronic F-127.

Photodynamic Therapy treatment of onychomycosis with Aluminium-Phthalocyanine Chloride nanoemulsions: A proof of concept clinical trial.

The conventional treatment of onychomycosis, a common fungal infection, consists in the use of local and systemic drugs for 4-6 months. This long protocol is often ineffective due to patient compliance, and usually promotes important collateral effects such as liver and kidney failure. As the alternative, Photodynamic Therapy (PDT) has been used as a noninvasive alternative local treatment for onychomycosis due to the reduction of systemic side effects, fact indicates their use for patients undergoing other systemic treatments.

Bronchial fistula closure with negative pressure wound therapy: a feasible and cost-effective treatment.

Treatment of bronchial fistula (BF) after pulmonary lobectomy is a challenge. Often, patients require long hospital stay, have recurrent empyema and pneumonia, are susceptible to sepsis, often need broad-spectrum antibiotics, as well as various surgical approaches. With the advent and growing evidence of the benefits of negative pressure therapy (NPT), its use in some patients with BF has been reported with encouraging results concerning its feasibility and cost-effectiveness.