Quantitative and qualitative outcomes associated with inpatient addiction consultation: a scoping review.

Rates of acute care use, including hospital admission and readmission, are high for people who misuse substances. Hospitalization provides a valuable opportunity for intervention, but addiction treatment is often not addressed in the inpatient setting. Addiction consult services are a novel intervention intended to change hospital practices.

Initiation and rapid titration of methadone and slow-release oral morphine (SROM) in an acute care, inpatient setting: a case series.

Background: Methadone titration in an outpatient setting typically involves initiation with subtherapeutic doses with slow titration to mitigate the risks of respiratory depression and overdose. In pregnancy, and generally, subtherapeutic doses of methadone and slow titrations are associated with poorer outcomes in terms of treatment retention and ongoing illicit opioid use. We aim to describe rapid titration of OAT in an inpatient setting for pregnant injection opioid users with high opioid tolerance secondary to a fentanyl-based illicit drug supply.

Collection and Use of Social Determinants of Health Data in Inpatient General Internal Medicine Wards: A Scoping Review.

Background: There is growing interest in incorporating social determinants of health (SDoH) data collection in inpatient hospital settings to inform patient care. However, there is limited information on this data collection and its use in inpatient general internal medicine (GIM). This scoping review sought to describe the current state of the literature on SDoH data collection and its application to patient care in inpatient GIM settings.

A comparison of acoustic and articulatory parameters for the GOOSE vowel across British Isles Englishes.

This study quantifies vocalic variation that cannot be measured from the acoustic signal alone and develops methods of standardisation and measurement of articulatory parameters for vowels. Articulatory-acoustic variation in the GOOSE vowel was measured across 3 regional accents of the British Isles using a total of 18 speakers from the Republic of Ireland, Scotland, and England, recorded with synchronous ultrasound tongue imaging, lip camera, and audio. Single co-temporal measures were taken of tongue-body height and backness, lip protrusion, F1, and F2.

Recurrent Endocarditis in Persons Who Inject Drugs.

Background: Infective endocarditis (IE) is increasing among persons who inject drugs (PWID) and has high morbidity and mortality. Recurrent IE in PWID is not well described.

Methods: This was a retrospective cohort study conducted between February 2007 and March 2016.

Clinical Characteristics and Factors Associated With Mortality in First-Episode Infective Endocarditis Among Persons Who Inject Drugs.

Importance: Persons who inject drugs (PWID) represent a distinct demographic of patients with infective endocarditis. Many centers do not perform valvular surgery on these patients owing to concerns about poor outcomes. Addiction services are underused in hospitals.

Variability in exercise capacity and metabolic response during endurance exercise after a low carbohydrate diet.

The impact of altered blood glucose concentrations on exercise metabolism and performance after a low carbohydrate (CHO) diet was investigated. In random order, 1 wk apart, 9 trained men underwent euglycemic (CI) or placebo (PI) clamps, while performing up to 150 min of cycling at 70% VO2(max), after 48 h on a low CHO diet. The range in improvement in endurance capacity with glucose infusion was large (28 +/- 26%, P < 0.

Summer pheasant's eye (Adonis aestivalis) poisoning in three horses.

Three horses died as a result of eating grass hay containing summer pheasant's eye (Adonis aestivalis L.), a plant containing cardenolides similar to oleander and foxglove. A 9-year-old thoroughbred gelding, a 20-year-old appaloosa gelding, and a 5-year-old quarter horse gelding initially presented with signs of colic 24-48 hours after first exposure to the hay.

Evaluation of peritoneal fluid pH, glucose concentration, and lactate dehydrogenase activity for detection of septic peritonitis in horses.

Objective: To determine whether peritoneal fluid pH, glucose concentration, and lactate dehydrogenase activity can be used to differentiate horses with septic peritonitis from those with nonseptic peritonitis.

Design: Prospective study.

Animals: 46 horses, including 10 healthy horses, 15 horses with septic peritonitis, and 21 horses with nonseptic peritonitis.

Photic headshaking in the horse: 7 cases.

Seven horses with headshaking are described. No physical abnormalities were detected in any of the cases. Six of these horses had onset of clinical signs in the spring.

Resolution of a left ureteral stone using electrohydraulic lithotripsy in a thoroughbred colt.

A 3-year-old Thoroughbred colt was presented for evaluation of azotemia and anorexia. Physical examination revealed a ureterolith in the left ureter, approximately 10 cm from the bladder, which was thought to obstruct urine flow by approximately 90% when viewed cystoscopically. Ultrasonographic examination of both kidneys revealed indistinct corticomedullary junctions, and the right kidney was more hyperechoic.

Behavioral cross-sensitization between cocaine and enkephalin in the A10 dopamine region.

The motor stimulant effect produced by cocaine and the injection of opioids onto A10 dopamine neurons is thought to be mediated by an increase in dopaminergic transmission in mesolimbic dopamine terminal fields such as the nucleus accumbens. Following daily administration, the behavioral stimulant effect of both cocaine and intra-A10 injection of opioids is augmented. The data in this report demonstrate that rats receiving daily injection of enkephalin analogue into the A10 have an enhanced motor stimulant response to intraperitoneal cocaine, but not to saline.

Gonadotropin-releasing hormone-induced alteration of bovine corpus luteum function.

Two experiments were conducted to evaluate effects of gonadotropin-releasing hormone (GnRH) on the function of the bovine corpus luteum during the estrous cycle. In Experiment 1, 10 beef heifers were assigned randomly into two groups; each heifer served as her own control. Heifers in Group I (n = 5) were injected i.