Risk score to stratify children with suspected serious bacterial infection: observational cohort study.

Objectives: To derive and validate a clinical score to risk stratify children presenting with acute infection.

Study Design And Participants: Observational cohort study of children presenting with suspected infection to an emergency department in England. Detailed data were collected prospectively on presenting clinical features, laboratory investigations and outcome.

Evaluation of temperature-pulse centile charts in identifying serious bacterial illness: observational cohort study.

Background: Distinguishing serious bacterial infection (SBI) from milder/self-limiting infections is often difficult. Interpretation of vital signs is confounded by the effect of temperature on pulse and respiratory rate. Temperature-pulse centile charts have been proposed to improve the predictive value of pulse rate in the clinical assessment of children with suspected SBI.