The use of clinical guidelines for referral of patients with lesions suspicious for oral cancer may ease early diagnosis and improve education of healthcare professionals.

Unlabelled: Early diagnosis and referral of oral cancer is essential. Successful implementation of clinical guidelines must include current practitioners and students.

Objective: To evaluate the diagnostic accuracy of students at oral cancer screening and to assess the effectiveness of clinical referral guidelines.

Oxidant/antioxidant interactions of nicotine, Coenzyme Q10, Pycnogenol and phytoestrogens in oral periosteal fibroblasts and MG63 osteoblasts.

Background: There is a growing awareness that oxidative stress may play a role in periodontal disease. The aim of this investigation was to evaluate potential oxidant/antioxidant interactions of nicotine with antioxidants (Coenzyme Q10 (CoQ), Pycnogenol and phytoestrogens in a cell culture model.

Methods: Duplicate incubations of human periosteal fibroblasts and osteoblasts were performed with 14C-testosterone as substrate, in the presence or absence of CoQ (20 microg/ml), Pycnogenol (150 microg/ml), and phytoestrogens (10 and 40 microg/ml), alone and in combination with nicotine (250 microg/ml).

Isolated gingival metastasis from hepatocellular carcinoma mimicking a pyogenic granuloma.

Background: Oral metastatic tumours are uncommon and account for approximately 1% of malignant oral neoplasms.

Results: If the cases where the oral location is in the jawbone, with secondary invasion to the oral soft tissue, are excluded, only 10 cases of gingival metastasis from hepatocellular carcinoma (HCC) have been previously reported in the literature. The clinicopathologic features of an HCC with gingival metastasis are reported.