[Cervical cancer before 35 years of age: epidemiological and prognostic aspects. Retrospective study of 46 cases of cervical cancer before 35 years of age in a series of 449 cases in stages IA2 and IV].

Objective: To investigate the diagnosis and prognosis aspects of carcinoma of the cervix in a group of young patients less 35 years old, not very clear in literature.

Study: Retrospective and comparative diagnostic and prognostic study. This study is related to the epidemiology and prognosis of such cervical cancer in young women.

[Tubal sterility. What treatment to propose: IVF or surgery?].

The results of IVF in cases of tubal sterility are compared with those of surgery (macro- or micro-surgery, coelio-surgery). This analysis includes a continuous series of 1051 attempted pregnancies in 640 women (with or mixed tubal sterility with or without endometriosis). After an average 1.

[Treatment of in situ ductal cancers of the breast].

According to the most recent studies reported in the literature, and those carried out in a trial carried out in Grenoble and Lyon (France) involving 210 in situ cancers of the breast, the respective indications for conservative and radical treatment are proposed for in situ duct cancers. The preferred orientation towards the most conservative treatment possible can be decided only after the prospective studies which are currently being evaluated in both the USA and in Europe.

[Absence of peritonization after pelvic cancer surgery. Results in 157 cases].

Pelvic lymphadenectomy for genital cancer can lead to complications: particularly lymphoceles, post-operative fever, thromboembolism and lymphoedema. We compared two groups in a series of 157 patients treated by extended lymphadeno-colpo-hysterectomy for cancer of the uterine cervix, of the endometrium, of the ovary, of the vagina: Group I: 108/157 patients: visceral peritonization: lymphoceles: 23.1%, post-operative fever: 35.

[Cancer and nipple discharge].

The authors, in a retrospective study, have looked at the clinical and paraclinical parameters that suggest that a cancer may be present when there is a nipple discharge. By using logistic regression on these criteria a model has been able to be constructed with four variables (bloody discharge, and associated palpable tumour, a suspicious mammographic appearance and atypical or proliferating cells in cytology). The probability of a cancer being present varies between three per thousand when none of the four variables are present to 99.

[Hysteroplasty in 1986. Technics and indications].

Hysteroplasty described by Bret in 1959 represents the procedure of choice in cases of bifid uterus with infertility secondary to repeated interruptions of pregnancy or complicated deliveries. This technique, of which we will remind the main steps, gives excellent results as demonstrated in a joint series from the Gynecological and Obstetrical Clinics of Hopital Edouard Herriot. In view of these good results, it seems that the indications of hysteroplasty should be broader than before in order to prevent the risks inherent in repeated interruptions of pregnancy and complicated deliveries.

[The principal genital malformations. Therapeutic aspects].

Some of the malformations affecting the female genital system are discovered too late and these may have serious repercussions on the subsequent genital activity of the adult woman. These abnormalities include partial aplasia and, in particular, total or unilateral menstrual retention. Obstructive malformations of this type (diaphragms, segmental atresia, unilateral menstrual retention or retention affecting both sides of the uterus, aplasia, isolated vagina etc.

[Estrogens and the endometrium].

A large number of studies have drawn attention to the multiplication of the number of endometrial cancers in women under oestrogens. All these retrospective studies are concordant, but the majority can be the object of criticisms and do not necessarily carry conviction. Oestroprogestational associations seem, on the contrary, to protect, in a certain measure, against the appearance of carcinoma of the endometrium.

[Cytogenic chorionic nodule of the uterus].

The authors report five observations of endometrial stromal nodules. These nodules are composed of cells identical to those of the endometrial stroma. They constitute the benign form of endometrial stromal tumors.

[Hysteroplasty for hemi-uterus and divided uterus. Apropos of 45 cases].

The authors present a series of 45 plastic operations for bicornuate uterus. Three women were operated on for functional symptoms, eight for sterility of which seven were primary, and thirty four for infertility. They are sorry that three women were lost to follow up.

Structure and composition of microcalcifications in benign and malignant lesions of the breast: study by light microscopy, transmission and scanning electron microscopy, microprobe analysis, and X-ray diffraction.

Microcalcifications previously located by radiography were extracted from 25 fresh specimens obtained from patients who had undergone tumorectomy or systematized mammary exeresis. Two principal types of microcalcifications were distinguished: Type I microcalcifications were amber in color and generally crystalline on scanning electron microscopy, with only one calcium peak on microprobe analysis; x-ray diffraction revealed that weddellite was involved. Type II microcalcifications were whitish, nonbirefringent under polarized light, and generally ovoid or fusiform, with two peaks, one calcium and the other phosphorus, on microprobe analysis; these microcalcifications were composed of calcium phosphate, the most characteristic form of which is hydroxyapatite, in the form of needles arranged in rosettes on transmission electron microscopy.

[Limitations of adnexal preservation in hysterectomy for benign lesions].

After recalling the possible risks of conservation of adnexae, the authors stress the advantages of such an approach. Taking into account the patient's age, ovarian disease, certain hormonal conditions and the risks of cancer, the authors generally tend to conserve ovarian function, unless there are absolute or relative contra-indications, such as those discussed by the authors.

[Basement membranes of epithelial tumors of the ovary. Histochemical and immunohistochemical study using antibodies to collagen IV, III, I and to laminin].

Thirteen ovarian tumours were the subject of a histochemical and immunohistochemical study using antibodies to collagen IV, III, I, and to laminin. Our study shows that it is not possible to assess the integrity of the basement membrane using simple histochemical methods (P.A.

[Value of differential cytology in the diagnosis of preclinical forms of cervix uteri cancer].

The value of "differential cytology" in the diagnosis of preclinical carcinoma of the cervix uteri was assessed from serial sections of operative specimens in a series of 452 patients. Although not absolute, this value was found to be considerable. Used to supplement colposcopy-guided biopsy, it makes it possible to decide on the therapeutic approach (notably simple destruction by laser) without having recourse to conization.

[Ovarian cancer: anatomo-clinical classifications].

There are important barriers in the correct evaluation of the anatomic involvement of malignant ovarian tumors. Nevertheless, it seems advisable to rationalise the criteria of involvement. The authors relate the past classifications of Heyman, Helsel, Munnel, Davis, Gellé, Rutledge and Burns.

Simultaneous onset of ulcerative colitis in the rectum and in a segment of colon used for colpopoiesis: report of a case.

A patient is described in whom a segment of colon used to construct an artificial vagina was therefore removed from intestinal continuity and was affected by typical idiopathic ulcerative colitis. The onset of disease was simultaneous in this loop of colon and in the rectum. There was no evidence of local infection.

[Uterine and sigmoid perforations following voluntary interruption of pregnancy by aspiration. A case report (author's transl)].

A recent case of mixed uterine and colic perforations associated with generalized peritonitis is reported, the lesions developing within the context of the digestive complications of the method known as aspiration for voluntary interruption of pregnancy. The frequency, severity, and treatment of these lesions are described, urgent laparotomy being necessary to correct both abdominal digestive tract and genital lesions. Prevention of these complication technique.

[Prolapse after hysterectomy. A study of 45 cases (author's transl)].

The authors report 45 cases of prolapse occurring after hysterectomy (26 after subtotal hysterectomy, 9 after total abdominal hysterectomy and 10 after total vaginal hysterectomy). These prolapses are rare and their incidence does not seem to vary with the type of hysterectomy that preceded them. although in some cases hysterectomy could be incriminated as the cause of the prolapse, in the majority of cases the reason was a prolapse that had been neglected when the hysterectomy had been carried out, or a prolapse that appeared a long time after hysterectomy because of the inevitable ageing of the supporting tissues of the pelvis.