Publications by authors named "Rochelle Hardie"

Article Synopsis
  • - Histoplasma capsulatum is a fungal pathogen found mainly in the Mississippi and Ohio River Valleys, as well as parts of Central and South America, and can reactivate in people with weakened immune systems.
  • - A case study describes a 72-year-old man who developed a painful tongue ulcer after starting immunosuppressive treatment for arthritis, revealing a latent infection with H. capsulatum that he likely contracted years earlier during military service in Central America.
  • - This case emphasizes the need for healthcare providers to be aware of the risks of histoplasmosis in patients with potential exposure to endemic areas, particularly before starting immunosuppressive therapies.
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Mycoplasma hominis and Ureaplasma species are urogenital mollicutes that can cause serious donor-derived infections in lung transplant recipients. Best practices for mollicute screening remain unknown. We conducted a single-center prospective study analyzing lung transplants performed from October 5, 2020, to September 25, 2021, whereby donor and recipient bronchoalveolar lavage (BAL) samples obtained at time of transplant underwent mollicute screening via culture and polymerase chain reaction (PCR).

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Mollicute infections, caused by Mycoplasma and Ureaplasma species, are serious complications after lung transplantation; however, understanding of the epidemiology and outcomes of these infections remains limited. We conducted a single-center retrospective study of 1156 consecutive lung transplants performed from 2010-2019. We used log-binomial regression to identify risk factors for infection and analyzed clinical management and outcomes.

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Patients with systemic lupus erythematosus (SLE) are at increased risk for infection including opportunistic infections. Fungal infection in particular can be difficult to diagnose and treat and often can be life-threatening in the immunocompromised patient. We present a case in which a patient with SLE presented to the hospital with shortness of breath and cough.

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A 38-year-old female of African-Caribbean origin presented with symptomatic anemia and was found to have hypoplastic thumbs and patchy hypopigmentation. Peripheral blood examination revealed pancytopenia and the bone marrow biopsy confirmed marrow hypoplasia. Fanconi anemia was later confirmed by flow cytometry and diepoxybutane testing.

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