Publications by authors named "Robyn McKenna"

Article Synopsis
  • * Laboratory tests confirmed the presence of a low-pathogenicity avian influenza virus (LPAIV) subtype H6N1, affecting 15 premises in Northern Ireland and spreading to 13 in the Republic of Ireland and six in Great Britain.
  • * The outbreak resulted in the culling of over 2 million birds to control the spread, highlighting the significant economic consequences and the need for swift action during LPAIV outbreaks.
View Article and Find Full Text PDF

This study investigates the role of transient receptor potential ankyrin 1 (TRPA1) in murine temporomandibular joint (TMJ) inflammatory hyperalgesia and the influence of the NLR family pyrin domain-containing 3 (NLRP3) inflammasome. Two distinct murine models of TMJ pain and inflammation (zymosan and CFA) were established. Spontaneous pain-like behaviours were observed as unilateral front paw cheek wipes.

View Article and Find Full Text PDF

Aim: To create an irreversible pulpitis gene signature from microarray data of healthy and inflamed dental pulps, followed by a bioinformatics approach using connectivity mapping to identify therapeutic compounds that could potentially treat pulpitis.

Methodology: The Gene Expression Omnibus (GEO) database, an international public repository of genomics data sets, was searched for human microarray datasets assessing pulpitis. An irreversible pulpitis gene expression signature was generated by differential expression analysis.

View Article and Find Full Text PDF