Publications by authors named "Robyn E Edgar"
Microbial communities in the world ocean are affected strongly by oceanic circulation, creating characteristic marine biomes. The high connectivity of most of the ocean makes it difficult to disentangle selective retention of colonizing genotypes (with traits suited to biome specific conditions) from evolutionary selection, which would act on founder genotypes over time. The Arctic Ocean is exceptional with limited exchange with other oceans and ice covered since the last ice age.
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- * Despite genome sequencing showing many genetically encoded natural products are still unknown, existing bioinformatics tools have been developed to predict nonribosomal peptides and polyketides from sequence data, while RiPPs remain poorly understood due to their complexity.
- * The study introduces a new algorithm that catalogs RiPP biosynthetic gene clusters, uncovering 30,261 RiPP clusters from over 65,000 prokaryotic genomes, leading to the identification of a rare