Front Artif Intell
March 2023
Introduction: Large pretrained language models have recently conquered the area of natural language processing. As an alternative to predominant masked language modeling introduced in BERT, the T5 model has introduced a more general training objective, namely sequence to sequence transformation, which more naturally fits text generation tasks. The monolingual variants of T5 models have been limited to well-resourced languages, while the massively multilingual T5 model supports 101 languages.
View Article and Find Full Text PDFNatural language processing (NLP) is an area of artificial intelligence that applies information technologies to process the human language, understand it to a certain degree, and use it in various applications. This area has rapidly developed in the past few years and now employs modern variants of deep neural networks to extract relevant patterns from large text corpora. The main objective of this work is to survey the recent use of NLP in the field of pharmacology.
View Article and Find Full Text PDFBackground: Cardiovascular disorders in general are responsible for 30% of deaths worldwide. Among them, hypertrophic cardiomyopathy (HCM) is a genetic cardiac disease that is present in about 1 of 500 young adults and can cause sudden cardiac death (SCD).
Objective: Although the current state-of-the-art methods model the risk of SCD for patients, to the best of our knowledge, no methods are available for modeling the patient's clinical status up to 10 years ahead.
Background: Machine learning (ML) and artificial intelligence are emerging as important components of precision medicine that enhance diagnosis and risk stratification. Risk stratification tools for hypertrophic cardiomyopathy (HCM) exist, but they are based on traditional statistical methods. The aim was to develop a novel machine learning risk stratification tool for the prediction of 5-year risk in HCM.
View Article and Find Full Text PDFVirtual population generation is an emerging field in data science with numerous applications in healthcare towards the augmentation of clinical research databases with significant lack of population size. However, the impact of data augmentation on the development of AI (artificial intelligence) models to address clinical unmet needs has not yet been investigated. In this work, we assess whether the aggregation of real with virtual patient data can improve the performance of the existing risk stratification and disease classification models in two rare clinical domains, namely the primary Sjögren's Syndrome (pSS) and the hypertrophic cardiomyopathy (HCM), for the first time in the literature.
View Article and Find Full Text PDFData preprocessing is an important component of machine learning pipelines, which requires ample time and resources. An integral part of preprocessing is data transformation into the format required by a given learning algorithm. This paper outlines some of the modern data processing techniques used in relational learning that enable data fusion from different input data types and formats into a single table data representation, focusing on the propositionalization and embedding data transformation approaches.
View Article and Find Full Text PDFIEEE Trans Neural Netw Learn Syst
May 2016
There are plenty of problems where the data available is scarce and expensive. We propose a generator of semiartificial data with similar properties to the original data, which enables the development and testing of different data mining algorithms and the optimization of their parameters. The generated data allow large-scale experimentation and simulations without danger of overfitting.
View Article and Find Full Text PDFObjective: Survey data sets are important sources of data, and their successful exploitation is of key importance for informed policy decision-making. We present how a survey analysis approach initially developed for customer satisfaction research in marketing can be adapted for an introduction of clinical pharmacy services into a hospital.
Methods And Material: We use a data mining analytical approach to extract relevant managerial consequences.
The International Basketball Federation (FIBA) recently introduced major rule changes that came into effect with the 2010/11 season. Most notably, moving the three-point arc and changing the shot-clock. The purpose of this study was to investigate and quantify how these changes affect the game performance of top-level European basketball players.
View Article and Find Full Text PDFArtif Intell Med
January 2004
We analyzed the data of a controlled clinical study of the chronic wound healing acceleration as a result of electrical stimulation. The study involved a conventional conservative treatment, sham treatment, biphasic pulsed current, and direct current electrical stimulation. Data was collected over 10 years and suffices for an analysis with machine learning methods.
View Article and Find Full Text PDFMed Biol Eng Comput
September 2001
The aim of the study is to determine the effects of wound, patient and treatment attributes on the wound healing rate and to propose a system for wound healing rate prediction. Predicting the wound healing rate from the initial wound, patient and treatment data collected in a database of 300 chronic wounds is not possible. After considering weekly follow-ups, it was determined that the best prognostic factors are weekly follow-ups of the wound healing process, which alone were found to predict accurately the wound healing rate after a minimum follow-up period of four weeks (at least five measurements of wound area).
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