Publications by authors named "Robles C"

Intraocular lenses (IOLs) are routinely used to replace cataractous crystalline lenses. Most current models have a biconvex design that reduces optical quality in the periphery since they are optimized only for central vision. Inverted meniscus IOLs are optimized to achieve similar optical performance to phakic eyes in the peripheral retina.

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Economic growth and urban sprawl in territorial systems produce an uneven distribution of infrastructure and services. This creates residential areas with high capital gains that are affordable only for the middle and upper classes. For lower-income groups, the only options are depressed urban areas with limited infrastructure.

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Purpose: Recent changes in the profile of liver transplant (LT) recipients include an increasing number of patients with metabolic-associated steatotic liver disease (MASLD), which is associated with obesity and cardiovascular risk. We aimed to investigate the trend in the presence of obesity among LT recipients and its association with cardiovascular risk.

Materials And Methods: Single-centre retrospective study, which included LT recipients between 2015 and 2020.

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Justice-involved individuals who reach the end of their full prison sentence no longer benefit from the supervision and rehabilitation services offered by probation or parole. Some of these individuals, who have been assessed to be a high risk for sexual and violent reoffending and deemed to pose a significant violence risk in the community if released, are placed on a judicial order in Canada, and police are asked to supervise and manage the risk of these individuals. In the current study, the files of 45 high-risk, justice-involved individuals, who completed their sentences, were released from a Canadian prison into the province of Alberta, and supervised by police under a judicial order, were reviewed for the presence of criminogenic and non-criminogenic needs over the first year of release.

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Variations in hematological profile in reptiles can be caused by multiple factors, including parasites presence. Our goals were to identify and morphologically describe blood cells of Liolaemus pacha and analyze their relationship with sex, body condition, individual reproductive/post-reproductive period and mite infestation. Blood smear analyses do not indicate the presence of hemoparasites, suggesting that the mites Neopterygosoma do not serve as vectors for these organisms, as has been proposed for other genera of ectoparasitic mites.

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Background: The COVID-19 pandemic led to a national lockdown and the interruption of all cancer preventive services, including cervical cancer screening. We aimed to assess the COVID-19 pandemic impact on opportunistic screening participation, abnormal cytology (ASCUS+) prevalence and screening interval in 2020 and 2021 within the Public Health System of Catalonia, Spain.

Methods: Individual data on cytology and HPV testing of women aged 25-65 from 2014 to 2021 were retrieved from the Information System for Primary Care Services (SISAP).

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Introduction: Infections in patients with cirrhosis are associated with high morbidity and mortality. Rifaximin is an antibiotic used to treat and prevent hepatic encephalopathy (HE); however, it has been suggested that it may play a crucial role in reducing infections in these populations.

Aim: To evaluate the role of rifaximin in preventing frequent cirrhosis-related infections [spontaneous bacterial peritonitis, pneumonia, urinary tract infection (UTI), and bacteremia], e infection, and all-cause mortality, as well as determining adverse effects and adherence to the drug.

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Unlabelled: Latin America presents a high prevalence of Helicobacter pylori(Hp) infection. Between1996-2003, the prevalence in Santiago, Chile, was 70%; recent studies indicate a decreasein this infection. Updating the frequency of Hp is crucial due to its associated health impact.

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Objective: The objective of this study was to identify factors associated with long-term opioid use and to assess the association between long-term use and death.

Study Design: Retrospective cohort study combining several population-wide databases and covering a population of five million inhabitants, including all adults who were initiated on opioid treatment from 2014 to 2018 for non-cancer pain.

Methods: We used logistic regression models to identify factors associated with chronic opioid use and carried out survival analyses using multivariable Cox regression modelling for all-cause mortality during follow-up using inverse probability of treatment weighting (IPTW) and propensity scores based on the probability of using opioids chronically.

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Two outbreaks of pine needle abortions in cattle are here reported for the first time in Argentina. The cases occurred in Chubut and Neuquén provinces in the Patagonia region, causing 29.6% and 9% of abortions in each herd respectively.

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On islands, flowering plants tend to be more generalist in their pollination needs, as insects (the main pollinators of flowering plants) are underrepresented in these ecosystems compared to the mainland. In addition, some vertebrate species that are typically insectivorous or granivorous on the mainland are forced to broaden their diet and consume other resources such as nectar or pollen on the islands. The shrub , with its large and colourful flowers, attracts different groups of potential pollinators.

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Background: Small bowel tumors (SBT) are infrequent and represent a small proportion of digestive neoplasms. There is scarce information about SBT in Latin America.

Aim: To describe the epidemiology, clinical characteristics, diagnostic methods, and survival of malignant SBTs.

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Background: The exploitative marketing of commercial milk formula (CMF) reduces breastfeeding, and harms child and maternal health globally. Yet forty years after the International Code of Marketing of Breast-Milk Substitutes (The Code) was adopted by WHO member states, many countries are still to fully implement its provisions into national law. Furthermore, despite The Code, worldwide CMF markets have markedly expanded.

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Article Synopsis
  • - Pluripotent stem cells (PSCs) are being explored as a source for off-the-shelf T cell immunotherapies, but their differentiation into mature T cells can lead to complications if not properly managed.
  • - Researchers successfully generated mature T cells from genetically edited PSCs that lack specific T cell receptors (TCRs) and class I major histocompatibility complexes, using a combination of human and murine cells for T cell maturation.
  • - The study found that these edited T cells demonstrated significantly improved tumor control in mouse models compared to those with intact TCRs, suggesting a promising approach for enhancing T cell immunotherapies derived from PSCs.
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Urbanization is one of the main threats to biodiversity. However, some urban green spaces could act as refuges for urban fauna if the composition of the flora were less horticultural and if a less intensive management strategy is adopted. Among the taxa, butterflies are experiencing a strong decline from European to regional scales.

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Article Synopsis
  • The study aimed to assess the effectiveness and quality of new intraocular lenses (IOLs) designed for presbyopia correction in patients undergoing cataract surgery.
  • A total of 60 eyes from 30 patients were implanted with two types of IOLs (Art40 and Art70) and were evaluated for visual acuity and patient-reported outcomes related to vision quality and spectacle dependence.
  • Results showed that most patients achieved excellent vision without glasses, with significant depth of focus and minimal reports of visual disturbances such as glare or halos.
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The cerebellum is known to play an important role in the coordination and timing of limb movements. The present study focused on how reach kinematics are affected by cerebellar lesions to quantify both the presence of motor impairment, and recovery of motor function over time. In the current study, 12 patients with isolated cerebellar stroke completed clinical measures of cognitive and motor function, as well as a visually guided reaching (VGR) task using the Kinarm exoskeleton at baseline (∼2 weeks), as well as 6, 12, and 24-weeks post-stroke.

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Background: The updated Sydney system biopsy protocol (USSBP) standardizes the sampling of gastric biopsies for the detection of preneoplastic conditions (e.g., gastric intestinal metaplasia [GIM]), but the real-world diagnostic yield is not well-described.

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The human genome encodes approximately 20,000 proteins, many still uncharacterised. It has become clear that scientific research tends to focus on well-studied proteins, leading to a concern that poorly understood genes are unjustifiably neglected. To address this, we have developed a publicly available and customisable "Unknome database" that ranks proteins based on how little is known about them.

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Objective: To identify individual and initial prescription-related factors associated with an increased risk for opioid-related misuse, poisoning and dependence (MPD) in patients with non-cancer pain.

Methods: Cohort study linking several databases covering 5 million inhabitants of the region of Valencia, Spain, including all adults initiating prescription opioids in the period 2012-2018. To ascertain the association between the characteristics of the initial prescription choice and the risk of opioid MPD, we used shared frailty Cox regression models.

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This study is the first report on mycosynthesis of silver nanoparticles (NPs) using psychrotrophic Antarctic filamentous fungi, and the first report regarding Tulasnella (Basidiomycota). In this work, the ability to synthesize silver NPs from cell free filtrates of strains of Tulasnella albida isolated from Antarctica was assessed. All fungal filtrates were capable of synthesizing silver NPs with the addition of AgNO.

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The oxidized low-density lipoprotein receptor 1 (LOX-1) is one of the most important receptors for modified LDLs, such as oxidated (oxLDL) and acetylated (acLDL) low-density lipoprotein. LOX-1 and oxLDL are fundamental in atherosclerosis, where oxLDL/LOX1 promotes ROS generation and NF-κB activation inducing the expression of IL-6, a STAT3 activator. Furthermore, LOX-1/oxLDL function has been associated with other diseases, such as obesity, hypertension, and cancer.

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The role of lizards as potential pollinators on islands has been documented for either one or a few plants in different parts of the world, but it has never been assessed for an entire plant community. Here, we quantified interaction rate by lizards and evaluated intraspecific differences in the use of flowers on Cabrera Gran (Cabrera archipelago, Balearic Islands) by means of visual observations, automated cameras and the analysis of pollen grain samples. Overall, we recorded interactions of the Balearic wall lizard () with flowers of 44 plant species, 72.

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