Publications by authors named "Robin S K Park"
J Proteome Res
December 2023
Article Synopsis
- SARS-CoV-2, the virus responsible for COVID-19, infects human airway cells by binding its spike protein to the ACE2 receptor on those cells.
- Researchers used advanced techniques to discover that the spike protein interacts with various host proteins, including laminin and thrombospondin, which could impact the virus's ability to infect cells.
- The study found that specific proteins preferentially combined with the original D614 spike variant over the mutated G614 variant, suggesting that this could allow the virus to infect a wider range of cells beyond just those that express ACE2.
