Publications by authors named "Robin M Ward"
Article Synopsis
- HER2-targeted therapies trastuzumab (T) and lapatinib (L) are effective against HER2-positive breast cancer, but many patients develop resistance, prompting this study to explore the mechanisms behind this resistance.
- A panel of 13 HER2-positive cell lines was used to evaluate resistance, identifying both de novo and acquired resistance through long-term drug exposure, while assessing hormone receptor (ER) pathway interactions and cellular responses to different treatments.
- Findings revealed that increased levels of ER or its products were linked to resistance, and while L-resistant lines could still be targeted through HER2 inhibition, they eventually shifted reliance from ER to the HER network, complicating treatment strategies with potential therapeutic implications for combining endocrine
Although a growing body of scholarly work explores the unique utility and therapeutic uses of psychological assessment, less work has focused specifically on feedback, with few studies that have explored empirically the underlying processes that may describe the role of feedback in a successful assessment. The purpose of this project was to add to the discourse on this topic by engaging in an empirical study exploring assessee and assessor experiences of significant events in psychological assessment feedback. The methodology is qualitative and modeled after significant events research in the study of psychotherapy process.
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