Publications by authors named "Robin L Dietz"
Article Synopsis
- Ki67 is a key biomarker in breast cancer but struggles with consistent measurement between labs, prompting research into automated digital image analysis (DIA).
- The study assessed Ki67 levels using specially prepared slides from 30 breast cancer patients, with analysis conducted by 17 labs to evaluate consistency in scoring.
- Results showed a strong correlation between consecutive sections, but core biopsy samples had notably higher Ki67 scores than whole sections, indicating that core biopsies may provide a more accurate biological status of the tumor.
Article Synopsis
- Developing a deep learning algorithm can help differentiate between small cell lung carcinoma (SCLC) and large cell neuroendocrine carcinoma (LCNEC) in cytology, which is often challenging.
- The study involved analyzing a variety of cytology samples (including smears and biopsies) from archived cases and training three different deep learning models based on the staining methods used.
- Results showed the algorithm achieved high accuracy in classifying the cancers, indicating its potential, but more extensive research with larger datasets is needed for improvement.
Systematic Review of the Use of Telepathology During Intraoperative Consultation.
Am J Clin Pathol
January 2020
Objective: To compare studies that used telepathology systems vs conventional microscopy for intraoperative consultation (frozen-section) diagnosis.
Methods: A total of 56 telepathology studies with 13,996 cases in aggregate were identified through database searches.
Results: The concordance of telepathology with the reference standard was generally excellent, with a weighted mean of 96.
Review of the use of telepathology for intraoperative consultation.
Expert Rev Med Devices
December 2018
Introduction: The use of telepathology in intraoperative consultations has been increasing due to limited time and availability of pathologists, and the demand for increased access to pathology subspecialists in difficult cases. The five main categories of telepathology are (1) static, (2) dynamic, (3) robotic, (4) whole slide imaging (WSI), and (5) hybrid methods. The majority of these methods have been found to offer diagnostic accuracy rates similar to conventional microscopy, at the cost of slightly prolonged time to evaluate slides.
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