Visual working memory impairments for single items following medial temporal lobe damage.

A growing body of research indicates that the medial temporal lobe (MTL) is essential not only for long-term episodic memory but also for visual working memory (VWM). In particular, recent work has shown that the MTL is especially important for VWM when complex, high-resolution binding is required. However, all of these studies tested VWM for multiple items which invites the possibility that working memory capacity was exceeded and patient impairments instead reflected deficits in long-term memory.

The effects of face inversion on perceiving- and sensing-based change detection.

Face perception is more difficult when faces are inverted compared to when they are upright. However, it is not known whether face inversion disrupts the ability to make perceiving-based discriminations (i.e.

The medial temporal lobe supports sensing-based visual working memory.

It is well established that the medial temporal lobe (MTL), including the hippocampus, is essential for long-term memory. In addition, recent studies suggest that the MTL may also support visual working memory (VWM), but the conditions under which the MTL plays a critical role are not yet clear. To address this issue, we used a color change detection paradigm to examine the effects of MTL damage on VWM by analyzing the receiver operating characteristics of patients with MTL damage and healthy age- and education-matched controls.