Publications by authors named "Robin Deleris"
Background: Morphine relieves dyspnea in various clinical circumstances. Whether or not this applies to patients admitted to intensive care units (ICUs) for acute respiratory failure (ARF) is unknown. We evaluated the efficacy and safety of low-dose morphine on dyspnea in patients admitted to the ICU for ARF.
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- The study examines how sensory interventions, such as music and air flux stimulation, can help relieve dyspnoea (difficulty breathing) in critically ill patients on mechanical ventilation.
- Researchers found that increasing pressure support on the ventilator significantly reduced dyspnoea, as did auditory stimulation with music compared to pink noise, and facial air flow compared to limb air flow.
- The findings suggest that these sensory interventions could effectively alleviate dyspnoea in ventilated patients without needing medications or increasing ventilator support, which is important for patient care protocols.
Article Synopsis
- Dyspnea is a common and severe issue for ICU patients with acute respiratory failure, and it negatively impacts their prognosis and mental health.
- This study tests the hypothesis that low-dose opioids, specifically morphine, can effectively reduce dyspnea in these patients by comparing results to a placebo in a controlled trial.
- The trial involves 22 patients randomly assigned to either receive morphine or a placebo, and will measure the intensity of dyspnea over a 24-hour period using a visual analog scale.
Background: The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) outbreak is spreading worldwide. To date, no specific treatment has convincingly demonstrated its efficacy. Hydroxychloroquine and lopinavir/ritonavir have potential interest, but virological and clinical data are scarce, especially in critically ill patients.
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