Is periodontitis a risk indicator for cancer? A meta-analysis.

Background: The aim of the present systematic review was to evaluate the hypothesis of an association between periodontitis and the development of cancer.

Methods: Two reviewers independently screened electronic and manual sources for pertinent articles. Primary outcome measures were the occurrence of neoplasm diagnosis in exposed and non-exposed groups, reported to evaluate association between cancer and periodontitis.

Coronally Advanced Flap With or Without Subepithelial Connective Tissue Graft for the Treatment of Single Recession: 5-Year Outcomes from a Comparative Study.

Gingival recession can cause an esthetic impairment or dentin hypersensitivity due to root surface exposure to the oral cavity. These conditions may require specific surgical interventions to achieve root coverage. This controlled clinical trial on 20 subjects compared coronally advanced flap (CAF) technique and CAF plus subepithelial connective tissue graft (CTG) for the treatment of single maxillary gingival recession.

Clinically Oriented Patient Maintenance Protocol: A Clinical Consensus of Experts.

The aim of the present survey was to define the most appropriate recall regimen and professional maintenance care protocol, identifying the main relative issues, based on a consensus of experts with long-term clinical experience. The survey consisted of 14 clinically relevant focused questions. The answers of each expert were aggregated to formulate clinical recommendations.

Efficacy of platelet concentrates in bone healing: A systematic review on animal studies - Part B: Large-size animal models.

In the presence of large bone defects, delayed bone union, or nonunion and fractures, bone reconstruction may be necessary. Different strategies have been employed to enhance bone healing among which the use of autologous platelet concentrates (APCs). Due to the high content of platelets and platelet-derived bioactive molecules (e.

Efficacy of platelets in bone healing: A systematic review on animal studies.

In presence of large bone defects, delayed bone union, non-union, fractures, and implant surgery, bone reconstruction may be necessary. Different strategies have been employed to enhance bone healing among which the use of autologous platelet concentrates. Due to the high content of platelets and platelet-derived bioactive molecules (e.

Osseointegration of Titanium Implants With Different Rough Surfaces: A Histologic and Histomorphometric Study in an Adult Minipig Model.

Background: Many chemical and physical modifications of titanium surfaces were introduced, aiming at improving surface bioactivity, but few comparative evidence exists.

Objective: To evaluate histologically in minipigs the osseointegration of implants made of commercially pure (CP) titanium or titanium alloy, treated by different roughening procedures.

Material And Methods: Three sandblasted acid-etched (SA) surfaces, 2 anodized (AN), and 1 double acid-etched (DAE) were compared.

Histomorphometric Results After Postextraction Socket Healing with Different Biomaterials: A Systematic Review of the Literature and Meta-Analysis.

Purpose: The aim of this systematic review was to investigate which material is the most effective bone substitute for alveolar bone healing by evaluating histomorphometric outcomes after healing of postextraction sockets in humans.

Materials And Methods: A manual and electronic search (PubMed, EMBASE, Cochrane Library) was performed using a search string prepared ad hoc. Data were statistically analyzed by calculating weighted mean percentage of new bone formation (primary outcome) and weighted mean percentage of residual biomaterial, soft/connective tissue, and nonmineralized tissue (secondary outcomes) in the biopsies.

Periodontal regeneration in aggressive periodontitis patients: A systematic review of the literature.

The aim of the present study was to systematically review the existing literature on periodontal regenerative procedures in individuals affected by aggressive periodontitis (AgP). An electronic and manual search was performed using an ad hoc prepared search string. All types of study designs were considered acceptable for inclusion.

Analysis of the 100 most-cited articles in periodontology.

Aim: The aim of the present study was to analyze two distinct biomedical electronic databases for the 100 most-cited articles in the field of periodontology.

Methods: Two electronic databases (Scopus [SCO] and Web of Science [WOS]) were used to retrieve lists of the 100 most-cited articles using appropriately-chosen keywords. The correlation between the number of citations and age of publication was evaluated statistically.

Antibiofilm activity of sandblasted and laser-modified titanium against microorganisms isolated from peri-implantitis lesions.

Infections due to biofilm-producing microorganisms are one of the main causes for the failure of dental implants. Increasing efforts have been made in order to develop new strategies to prevent biofilm formation. In this study, the biofilm development on a newly designed laser-modified titanium implant surface was evaluated and compared to that on conventional sandblasted titanium used in implant dentistry.

A Fusion between Domains of the Human Bone Morphogenetic Protein-2 and Maize 27 kD γ-Zein Accumulates to High Levels in the Endoplasmic Reticulum without Forming Protein Bodies in Transgenic Tobacco.

Human Bone Morphogenetic Protein-2 (hBMP2) is an osteoinductive agent physiologically involved in bone remodeling processes. A commercialized recombinant hBMP2 produced in mammalian cell lines is available in different clinical applications where bone regeneration is needed, but widespread use has been hindered due to an unfavorable cost/effective ratio. Protein bodies are very large insoluble protein polymers that originate within the endoplasmic reticulum by prolamine accumulation during the cereal seed development.

Maxillary Sinus Floor Elevation Using Platelet-Rich Plasma Combined With Either Biphasic Calcium Phosphate or Deproteinized Bovine Bone.

Purpose: Maxillary sinus floor elevation procedure has the objective of augmenting available bone in atrophic posterior maxilla to allow dental implants placement. The main aim of this prospective study was to evaluate clinically and histomorphometrically the performance of biphasic calcium phosphate (BCP) used in conjunction with platelet-rich plasma (PRP) compared with demineralized bovine bone matrix (DBBM) and PRP in sinus floor elevation surgery.

Materials And Methods: Patients candidate to sinus floor elevation were treated using either BCP and PRP or DBBM and PRP.

Antimicrobial properties of platelet-rich preparations. A systematic review of the current pre-clinical evidence.

In recent years autologous platelet concentrates (APCs) have become popular in several medicine fields, representing a valuable adjunct to regenerative surgical procedures. Beneficial effects in the control of postsurgical discomfort and infection have also been frequently reported, suggesting that APC may possess anti-inflammatory and antimicrobial properties. The aim of the present review was to summarize the current evidence regarding the antimicrobial effects of platelet concentrates, investigated by in vitro and animal studies.

Magnification devices for endodontic therapy.

Background: After the introduction of microsurgical principles in endodontics involving new techniques for root canal treatment, there has been a drive to enhance the visualisation of the surgical field. It is important to know if the technical advantages for the operator brought in by magnification devices such as surgical microscopes, endoscopes and magnifying loupes, are also associated with advantages for the patient in terms of improvement of clinical and radiographic outcomes. This version updates the review published in 2009.

Autologous Platelet Concentrates for Pulp and Dentin Regeneration: A Literature Review of Animal Studies.

Introduction: The purpose of this study was to evaluate the effectiveness of autologous platelet concentrates (APCs) in promoting pulp and dentin regeneration in animal models.

Methods: An electronic search was performed on MEDLINE, Embase, Scopus, SciELO, LILACS, and CENTRAL. Animal studies using APC as a root filling material after pulpectomy in mature or immature teeth were included.

Adverse pregnancy outcomes and periodontitis: A systematic review and meta-analysis exploring potential association.

Objective: The correlation between periodontal status and systemic conditions, among them pregnancy, is widely described in the scientific literature. The aim of the present systematic review of the literature was to evaluate periodontal diseases as an independent risk factor for adverse pregnancy outcomes.

Data: Case-control studies reporting pregnancy outcomes and periodontal status of the subjects were included.

Histomorphometric outcomes after lateral sinus floor elevation procedure: a systematic review of the literature and meta-analysis.

Objectives: The aim of the present systematic review of the literature was to evaluate biomaterials performances considering new bone formation estimated through histomorphometric analysis of bone biopsies from human subjects after maxillary sinus floor elevation.

Materials And Methods: An electronic and manual search was performed to retrieve articles showing histomorphometric data of bone biopsies performed after sinus floor elevation surgery. Recorded data were statistically analyzed evaluating percentage of new bone volume, residual biomaterial, and connective/soft tissues in the biopsies.

Erythritol-Enriched Air-Polishing Powder for the Surgical Treatment of Peri-Implantitis.

Peri-implantitis represents a major complication that can compromise the success and survival of implant-supported rehabilitations. Both surgical and nonsurgical treatment protocols were proposed to improve clinical parameters and to treat implants affected by peri-implantitis. A systematic review of the literature was performed on electronic databases.

Platelet-Rich Plasma and Deproteinized Bovine Bone Matrix in Maxillary Sinus Lift Surgery: A Split-Mouth Histomorphometric Evaluation.

Purpose: The purpose of this split-mouth controlled study was to evaluate and compare the amount of vital bone after lateral sinus lift surgery using either a mixture of pure platelet concentrate and deproteinized bovine bone mineral (test group) or solely deproteinized bovine bone as grafting material (control group).

Materials And Methods: Six patients with edentulous posterior maxilla and a residual ridge height of less than 4 mm were recruited in this study. Six months after grafting procedure, 2 bone biopsies per patient were taken bilaterally from the anterolateral sinus wall.

Autologous platelet concentrate for post-extraction socket healing: a systematic review.

Background: Autologous platelet concentrates are claimed to enhance hard and soft tissue healing due to the considerable amount of growth factors that are released after application in the surgical site. However, their actual efficacy for improving tissue healing and regeneration in oral surgery applications is controversial. Tooth extraction socket healing represents a proper model to study the effect of autologous platelet-enriched preparations due to the concomitant occurrence of different processes of both hard and soft tissue healing.

Tilted trans-sinus implants for the treatment of maxillary atrophy: case series of 35 consecutive patients.

Purpose: To evaluate tilted trans-sinus implants for rehabilitation of the atrophic maxilla.

Materials And Methods: A case series of 35 patients (32 consecutive edentulous and 3 partially edentulous patients) treated with trans-sinus dental implants is presented. Edentulous patients received 4 or 6 implants depending on anatomic conditions and a 12-unit final restoration; partially edentulous patients received 2 implants supporting a 3-unit partial fixed bridge.

Immediate versus conventional loading of post-extraction implants in the edentulous jaws.

Purpose: This retrospective study deals with the issue of how to realize the transition from a failing dentition to an implant-supported prosthesis. The main aim was to assess the reliability of immediate implant and immediate loading (IL) protocols in the edentulous jaws. A further aim was to investigate the role of patient-related, implant-related, and surgery-related secondary variables in the occurrence of implant failure.

Implant-buccal plate distance as diagnostic parameter: a prospective cohort study on implant placement in fresh extraction sockets.

Background: The aim of this study is to investigate contour changes around immediate implants in fresh extraction sockets when different grafting procedures are performed, based on the distance between the external implant collar and the bony surface on the buccal plate (I-BP). A secondary aim is to assess the esthetic outcome via the implant esthetic score (IAS).

Methods: This prospective cohort study was performed in three centers.

Risk factor analysis following maxillary sinus augmentation: a retrospective multicenter study.

Purpose: Implant-supported rehabilitation of the atrophic posterior maxilla often necessitates maxillary sinus surgery to augment existing bone volumes. Recent systematic reviews have reported implant survival rates above 90% following sinus elevation. However, statistical assessment of the effect of anatomic factors, implant design and surface, individual risk factors, and complications related to sinus floor elevation procedures on implant survival through analyzing patient data has not yet been performed.