High coronary artery calcium scores pose an extremely elevated risk for hard events.

Objectives: We sought to assess the natural history of a cohort of asymptomatic individuals with very high (> or = 1,000) calcium scores (CSs) on a screening electron beam tomography (EBT) not submitted to further testing after the initial scan. We also compared the outcome of our prospective cohort with that of historical controls with severe abnormalities on myocardial perfusion imaging (MPI).

Background: Coronary calcium detected on EBT imaging has been shown to correlate with the total plaque burden.