Acute subarachnoid hemorrhage associated with platelet storage pool disease and the hemoglobinopathy caused by beta-thalassemia minor.

We describe a case of acute subarachnoid hemorrhage with a complex blood-clotting mechanism and two negative angiographies. The patient was discharged from hospital with a presumptive diagnosis of idiopathic causes, but further analysis of the clinical history from the primary care provider prompted a hematologic analysis, which produced a diagnosis of platelet storage pool disease with alterations during the degranulation and aggregation functions. Electron microscopy revealed no ultrastructural abnormalities of platelet membranes, granules, or organelles.