Publications by authors named "Roberto Pariente-Rodriguez"
Article Synopsis
- The study focused on evaluating immunity in nursing home residents and staff in Madrid, Spain, amid the COVID-19 pandemic and vaccination efforts, revealing a high risk of infection and mortality among older adults, particularly residents.
- Results showed that residents had a significantly higher likelihood of contracting COVID-19 compared to staff, especially before vaccination.
- Despite robust vaccination, the presence of prior COVID-19 infections corresponded with increased antibody levels, but factors such as previous health status didn't correlate with infection rates or mortality in the cohort observed.
The aim of this study is to assess the relationship between myositis specific (MSA) and myositis associated (MAA) antibodies and diagnosis (including idiopathic inflammatory myopathies [IIM] and other systemic autoimmune diseases [SAID]), and to explore the impact of antibody signal intensity in diagnostic accuracy. We retrospectively reviewed all the serum samples obtained from patients tested for MSA/MAA by line immunoassay (LIA) between 01/01/2018 and 31/12/2020 in Ramón y Cajal University Hospital (Spain). Clinical true positive (CTP) MSAs and MAAs were defined as those patients with IIM or SAID with phenotypes expected of that MSA/MAA.
View Article and Find Full Text PDFHuman Leukocyte Antigen (HLA) includes a large set of genes with important actions in immune response against viral infection. Numerous studies have revealed the existence of significant associations between certain HLA alleles and the susceptibility and prognosis of different infectious diseases. In this pilot study we analyse the binding affinity between 66 class I HLA alleles and SARS-CoV-2 viral peptides, and its association with the severity of the disease.
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