Publications by authors named "Roberto Marin-Gil"
Objective: economic evaluation is a fundamental criterion when deciding a drug's place in therapy. The MADRE method (Method for Assistance in making Decisions and Writing Drug Evaluation Reports) is widely used for drug evaluation. This method was developed by the GENESIS group of the Spanish Society of Hospital Pharmacy (SEFH), including economic evaluation.
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- - The study aimed to survey the off-label treatments commonly used in oncohaematology and understand the procedures for authorizing them.
- - The survey revealed that 42.1% of hospitals require prior authorization for over 80% of off-label treatments, with the available evidence being the key factor influencing approval.
- - Findings indicate significant variability in how off-label treatments are utilized and authorized across hospitals, with many lacking clear criteria for determining clinical benefit or cost-effectiveness.
Trastuzumab emtansina (T-DM1) is an antibody-drug conjugate directed against the HER2 for the treatment of HER2+ mestastatic breast cancer (MBC), who has previously received trastuzumab plus a taxane. According to the results of the EMILIA trial versus lapatinib plus capecitabine T-DM1 shows an improvement in progression-free survival (PFS) and the overall survival (OS). It has a favorable profile reducing the incidence of grade 3-4 adverse reactions such as hand-foot syndrome and diarrhea.
View Article and Find Full Text PDFBackground: The place of monoclonal antibodies in metastatic colorectal cancer has not been clearly defined.
Objective: To determine the treatment pattern of monoclonal antibodies in colorectal cancer patients in the Andalusian Public Healthcare System.
Method: Data were collected from all patients treated with these drugs from July 2009 to December 2010 from pharmacy programs and medical records.
Aim Of The Review: To study the prevalence of drug interactions in hospital healthcare by reviewing literature.
Method: A review was carried out of studies written in Spanish and English on the prevalence of drug interactions in hospital care published in Pubmed between January 1990 and September 2008. The search strategy combined free text and MeSH terms, using the following keywords: "Drug interaction", "prevalence" and "hospital".
Background: The healthcare models developed for patients with multiple chronic diseases agree on the need for improving drug therapy in these patients. The issues of patient compliance, appropriateness of prescriptions and the reconciliation process are of vital importance for patients receiving multiple drug treatment.
Objective: To identify and select the most appropriate tools for measuring treatment compliance and appropriateness in multiple-disease patients, as well as the best reconciliation strategy.