Fully automatic segmentation of brain lacunas resulting from resective surgery using a 3D deep learning model.

The rapid and constant development of deep learning (DL) strategies is pushing forward the quality of object segmentation in images from diverse fields of interest. In particular, these algorithms can be very helpful in delineating brain abnormalities (lesions, tumors, lacunas, etc), enabling the extraction of information such as volume and location, that can inform doctors or feed predictive models. Here, we describe ResectVol DL, a fully automatic tool developed to segment resective lacunas in brain images of patients with epilepsy.

The emotional and psychiatric problems of adolescents on parole whose parents are substance users: A Brazilian cross-sectional study.

The aim of this study is to evaluate the associations between having parents with substance use problems, and having suffered neglect within the family, and behavioral problems (psychological and drug use) among adolescents. All the participants were enrolled on the socio-educational parole scheme, 'Assisted Freedom'. In this cross-sectional study, 150 adolescents were interviewed using the Drug Abuse Screening Test, Teen Addiction Severity Index, and Childhood Trauma Questionnaire.

Analysis of behavior of the wear coefficient in different layers of acrylic resin teeth.

Statement Of Problem: Analysis of the wear coefficient (k) of the superficial and deep layers of acrylic resin teeth can help predict denture durability, but little has been published on the wear coefficient of denture teeth.

Purpose: The purpose of this in vitro study was to determine the k value for the superficial and deep layers of the acrylic resin teeth of 6 different brands by using the fixed-ball microabrasive wear method.

Material And Methods: Six artificial tooth specimens of 4 commercial brands were tested: Artiplus IPN (Ar), Biotone IPN (Bi), Magister (Ma), Premium (Pr), Trilux (Tr), and SR Vivodent (Vi).

Susceptibly of to extracts.

is an important pathogen with worldwide distribution that causes severe economic loss of efficiency in broilers. This study evaluates the potential of organic extracts of two strains entomopathogenic fungus (CG71 and UNI40) as a biocontrol agent on and promotes the phytochemical investigation. The effective percentages of mortalities were 95.

The use of asymmetric distributions in average bioequivalence.

Generic drugs have been commercialized in numerous countries. Most of these countries approve the commercialization of a generic drug when there is evidence of bioequivalence between the generic drug and the reference drug. Generally, the pharmaceutical industry is responsible for the bioequivalence test under the supervision of a regulatory agency.

The growth hormone receptor exon 3 polymorphism is not associated with height or metabolic traits in healthy young adults.

Context: The GHR polymorphisms contribution to the interindividual variability in prenatal and postnatal growth as well as to metabolic traits is controversial.

Objective: The aim of this study is to analyze the association of the GHRfl/d3 polymorphism with prenatal and postnatal growth and metabolic outcomes in adult life and to compare the genotype distribution in different populations.

Design: 385 community healthy subjects followed from birth to adult life (23-25years old) were grouped according to birth size: small-SGA (n=130, 62 males), appropriate-AGA (n=162, 75 males) and large for gestational age-LGA (n=93, 48 males).

Effect of antiretroviral therapy including lopinavir/ritonavir or efavirenz on etonogestrel-releasing implant pharmacokinetics in HIV-positive women.

Objective: Data on the interaction between the etonogestrel (ENG) implant and antiretroviral therapy are lacking. We evaluated the effect of 2 highly active antiretroviral therapy (HAART) regimens (1 including efavirenz and the other ritonavir-boosted lopinavir) on the pharmacokinetic (PK) parameters of an ENG-releasing implant in HIV-positive women.

Design: Prospective nonrandomized PK study.

Postnatal growth and cardiometabolic profile in young adults born large for gestational age.

Context: The association between large for gestational age (LGA) phenotype, postnatal growth and cardiometabolic risk (CMR) in adult life remains unclear. The role of IGF1 genotype on LGA-related outcomes in adult life is unknown.

Aim: To assess the postnatal growth, IGF-I levels, CMR and the influence of the 737.

Adiponectin: serum levels, promoter polymorphism, and associations with birth size and cardiometabolic outcome in young adults born large for gestational age.

Objective: To assess whether the -11391G>A polymorphism in the regulatory region of the adiponectin gene (ADIPOQ) is associated with birth size, postnatal growth, adiponectinemia, and cardiometabolic risk in adult life.

Design: Case-control study nested within a prospective cohort of 2063 community subjects born in 1978/1979 and followed since birth to date.

Methods: ADIPOQ -11391G>A genotype-phenotype associations were evaluated in 116 subjects born large for gestational age (LGA) and 392 gender-matched controls at birth (birth size), at 8-10 years (catch-down growth), and at 23-25 years of age (cardiometabolic profile).

Shear versus micro-shear bond strength test: a finite element stress analysis.

Objectives: This study aimed at comparing the stress distribution in shear and micro-shear test set-ups using finite element analysis, and suggesting some parameter standardization that might have important influence on the results.

Methods: Two-dimensional plane strain finite element analysis was performed using MSCPatran and MSCMarc softwares. Model configurations were based on published experimental shear and micro-shear test set-ups and material properties were assumed to be isotropic, homogeneous and linear-elastic.