Septic shock significantly affects children globally, leading to high hospitalisation and mortality rates, prompting the paediatric Surviving Sepsis Campaign to update guidelines in 2020 based on existing evidence.
Recent trials from low and middle-income countries (LMICs) have provided new insights into effective treatment options, such as fluid management and vasoactive infusions.
This viewpoint highlights the need for improved sepsis care in LMICs by addressing early recognition of septic shock, fluid resuscitation, and individualised treatment approaches using accessible monitoring tools.