Assessments scales for the evaluation of health-related quality of life in Parkinson's disease, progressive supranuclear palsy, and multiple system atrophy: a systematic review.

Background: The concept of wellbeing is expansive and intricate, making it challenging to define precisely. Similarly, the instruments employed to assess wellbeing are complex and multifaceted. Therefore, it is more appropriate to refer to the notion of wellbeing as Health-Related Quality of Life (HRQoL), which is the central focus of many measures used to assess the feeling of wellbeing.

Psychometric Characteristics of the Italian Version of the Revised Sociosexual Orientation Inventory.

Sociosexuality refers to the tendency to engage in uncommitted sexual behavior and has been dissected into three domains: sociosexual behavior, attitudes, and desire (Penke & Asendorpf, 2008), which led to the revised Sociosexual Orientation Inventory (SOI-R), which was validated on a German sample. The current research aimed at translating and validating an Italian version (I-SOI-R), administered to three distinct Italian participant groups. In the first sample (N = 710, females = 521, age = 18-59 years), we found evidence for a bifactor model, articulated in a general sociosexuality factor and three specific factors (behavior, attitudes, desire).

Measurement invariance across countries of the Test of Memory Strategies (TMS): A contribution to the cross-national validity study.

Previous literature showed a complex interpretation of recall tasks due to the complex relationship between Executive Functions (EF) and Long Term Memory (M). The Test of Memory Strategies (TMS) could be useful for assessing this issue, because it evaluates EF and M simultaneously. This study aims to explore the validity of the TMS structure, comparing the models proposed by Vaccaro et al.

Sensitivity of conventional cognitive tests in multiple sclerosis: Application of item response theory.

Background: Cognitive impairment (CI) is common in Multiple Sclerosis (MS), and its prevalence rate ranges between 22% and 70%. Because CI significantly impacts vocational status, caregiver burden, and quality of life, an accurate neuropsychological assessment is required. Three widely used and validated batteries for MS-associated CI are the Brief Repeatable Neuropsychological Battery (BRN-B), the Minimal Assessment of Cognitive Function (MACFIMS), and the Brief International Cognitive Assessment (BICAMS).

Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of Deficiency Disorder.

Mutations in the X-linked cyclin-dependent kinase-like 5 () gene cause a rare neurodevelopmental disorder characterized by early-onset seizures and severe cognitive, motor, and visual impairments. To date there are no therapies for deficiency disorder (CDD). In view of the severity of the neurological phenotype of CDD patients it is widely assumed that may influence the activity of a variety of cellular pathways, suggesting that an approach aimed at targeting multiple cellular pathways simultaneously might be more effective for CDD.