Imposex incidence in gastropod species from the Colombian Caribbean Coast reveals continued and widespread tributyltin contamination after its global ban.

Organotin compounds (OTCs), such as tributyltin (TBT) and triphenyltin (TPhT), are released in aquatic environments from antifouling coatings and can cause imposex, an abnormal condition where female snails develop male sexual characteristics. This study investigates temporal variations in imposex incidence along the Colombian Caribbean coast following the 2008 global ban on TBT-based antifouling paints. Over a 12-year period, we assessed imposex in 1,384 adults snails from six species (58% female and 42% male) during 2012, 2016, and 2023.

On the separation of enantiomers by drift tube ion mobility spectrometry.

Racemic mixtures of twelve common α-amino acids and three chiral drugs were tested for the separation of their enantiomers by drift tube ion mobility spectrometry (IMS)-quadrupole mass spectrometry (QMS) by introducing chiral selectors into the buffer gas of the IMS instrument. ()-α-(Trifluoromethyl)benzyl alcohol, (L)-ethyl lactate, methyl ()-2-chloropropionate, and the and enantiomers of 2-butanol and 1-phenyl ethanol were evaluated as chiral selectors. Experimental conditions were varied during the tests, including buffer gas temperature, concentration and type of chiral selectors, analyte concentration, electrospray (ESI) voltage, ESI solvent pH, and buffer gas flow rate.

Ion-shift reagent binding energy and the mass-mobility shift correlation in ion mobility spectrometry.

Rationale: Ion mobility spectrometry (IMS) detects illegal substances and explosives in airports, ports, and customs. This is complicated by false positives caused by overlapping peaks. Shift reagents selectively change ion mobilities through adduction with analyte ions.

Ion mobility spectrometry experiments should be carried out at high temperatures to reduce uncertainties in the measurement of reduced mobilities.

In ion mobility spectrometry (IMS), reduced mobility (K) is an identification parameter of gas-phase ions but, frequently, these values are different whether there is contamination with moisture and other volatile compounds or not. We studied the effect of 2-butanol as a contaminant in IMS using electrospray ionization-IMS-mass spectrometry. The ion mobilities of valinol, phenylalanine, and tryptophan were measured with 0.

Ion mobility spectrometry: the diagnostic tool of third millennium medicine.

Ion mobility spectrometry (IMS) is a fast, low cost, portable, and sensitive technique that separates ions in a drift tube under the influence of an electric field according to their size and shape. IMS represents a non-invasive and reliable instrumental alternative for the diagnosis of different diseases through the analysis of volatile metabolites in biological samples. IMS has applications in medicine in the study of volatile compounds for the non-invasive diagnose of bronchial carcinoma, chronic obstructive pulmonary disease, and other diseases analysing breath, urine, blood, faeces, and other biological samples.

Buffer gas additives (modifiers/shift reagents) in ion mobility spectrometry: Applications, predictions of mobility shifts, and influence of interaction energy and structure.

Ion mobility spectrometry (IMS) is an analytical technique used for fast and sensitive detection of illegal substances in customs and airports, diagnosis of diseases through detection of metabolites in breath, fundamental studies in physics and chemistry, space exploration, and many more applications. Ion mobility spectrometry separates ions in the gas-phase drifting under an electric field according to their size to charge ratio. Ion mobility spectrometry disadvantages are false positives that delay transportation, compromise patient's health and other negative issues when IMS is used for detection.

Caffeine and glucosamine mobility shifts by adduction with 2-butanol depended on interaction energy, charge delocalization, and steric hindrance in ion mobility spectrometry.

Ion mobility spectrometry (IMS) is an analytical technique that separates gas-phase ions drifting under an electric field according to their size to charge ratio. We used electrospray ionization-drift tube IMS coupled to quadrupole mass spectrometry to measure the mobilities of glucosamine (GH ) and caffeine (CH ) ions in pure nitrogen or when the shift reagent (SR) 2-butanol was introduced in the drift gas at 6.9 mmol m .

Shift reagents in ion mobility spectrometry: the effect of the number of interaction sites, size and interaction energies on the mobilities of valinol and ethanolamine.

Overlapping peaks interfere in ion mobility spectrometry (IMS), but they are separated introducing mobility shift reagents (SR) in the buffer gas forming adducts with different collision cross-sections (size). IMS separations using SR depend on the ion mobility shifts which are governed by adduct's size and interaction energies (stabilities). Mobility shifts of valinol and ethanolamine ions were measured by electrospray-ionization ion mobility-mass spectrometry (MS).

Deprotonation effect of tetrahydrofuran-2-carbonitrile buffer gas dopant in ion mobility spectrometry.

Rationale: When dopants are introduced into the buffer gas of an ion mobility spectrometer, spectra are simplified due to charge competition.

Methods: We used electrospray ionization to inject tetrahydrofuran-2-carbonitrile (F, 2-furonitrile or 2-furancarbonitrile) as a buffer gas dopant into an ion mobility spectrometer coupled to a quadrupole mass spectrometer. Density functional theory was used for theoretical calculations of dopant-ion interaction energies and proton affinities, using the hybrid functional X3LYP/6-311++(d,p) with the Gaussian 09 program that accounts for the basis set superposition error; analytes structures and theoretical calculations with Gaussian were used to explain the behavior of the analytes upon interaction with F.

Activated carbons from waste of oil-palm kernel shells, sawdust and tannery leather scraps and application to chromium(VI), phenol, and methylene blue dye adsorption.

Phenol, chromium, and dyes are continuously dumped into water bodies; the adsorption of these contaminants on activated carbon is a low-cost alternative for water remediation. We synthesized activated carbons from industrial waste of palm oil seed husks (kernel shells), sawdust, and tannery leather scraps. These materials were heated for 24 h at 600, 700 or 800°C, activated at 900°C with CO2 and characterized by proximate analysis and measurement of specific surface area (Brunauer-Emmett-Teller (BET) and Langmuir), and microporosity (t-plot).

Buffer gas modifiers effect resolution in ion mobility spectrometry through selective ion-molecule clustering reactions.

Rationale: When polar molecules (modifiers) are introduced into the buffer gas of an ion mobility spectrometer, most ion mobilities decrease due to the formation of ion-modifier clusters.

Methods: We used ethyl lactate, nitrobenzene, 2-butanol, and tetrahydrofuran-2-carbonitrile as buffer gas modifiers and electrospray ionization ion mobility spectrometry (IMS) coupled to quadrupole mass spectrometry. Ethyl lactate, nitrobenzene, and tetrahydrofuran-2-carbonitrile had not been tested as buffer gas modifiers and 2-butanol had not been used with basic amino acids.

Using a Buffer Gas Modifier to Change Separation Selectivity in Ion Mobility Spectrometry.

The mobilities of a set of common α-amino acids, four tetraalkylammonium ions, 2,4-dimethyl pyridine (2,4-lutidine), 2,6-di-tert-butyl pyridine (DTBP), and valinol were determined using electrospray ionization-ion mobility spectrometry-quadrupole mass spectrometry (ESI-IMS-QMS) while introducing 2-butanol into the buffer gas. The mobilities of the test compounds decreased by varying extents with 2-butanol concentration in the mobility spectrometer. When the concentration of 2-butanol increased from 0.

Ion mobility spectrometry for the rapid analysis of over-the-counter drugs and beverages.

In the pharmaceutical industry, there are increasing requirements for analytical methods in quality assessment for the production of drugs. In this investigation, ion mobility spectrometry (IMS) was used for the rapid qualitative separation and identification of active ingredients in generic over-the-counter drugs and food additives in beverages. The active ingredients determined in drugs were acetaminophen, aspartame, bisacodyl, caffeine, dextromethorphan, diphenhydramine, famotidine, glucosamine, guaifenesin, loratadine, niacin, phenylephrine, pyridoxine, thiamin, and tetrahydrozoline.

Chemical standards in ion mobility spectrometry.

In ion mobility spectrometry (IMS), reduced mobility values (K(0)) are used as a qualitative measure of gas phase ions, and are reported in the literature as absolute values. Unfortunately, these values do not always match with those collected in the field. One reason for this discrepancy is that the buffer gas may be contaminated with moisture or other volatile compounds.