A case report of male breast cancer in a very young patient: what is changing?

Male breast cancer accounts for 1% of all breast cancer cases, and men tend to be diagnosed at an older age than women (mean age is about 67 years). Several risk factors have been identified, such as genetic and hormonal abnormalities. The present study reported the case of a 25-year-old man who was diagnosed with an advanced invasive ductal carcinoma; however, he did not have any important risk factors.

Effectiveness of imiquimod 5% cream for treatment of extensive anogenital warts in a seven-year-old child.

Conventional treatment options for anogenital warts in prepubertal children rely on chemical and physical destruction methods that can be difficult and painful and frequently require the use of general anesthesia. Other approaches include the use of immunotherapies, as topical imiquimod and intralesional or systemic interferon. We report a 7-year-old girl with extensive anogenital warts who was successfully treated with topical 5% imiquimod cream.

Langerhans cells in cervical intraepithelial neoplasia related to smoking habits.

Objective: Compare the numerical densities of intraepithelial Langerhans cells of uterine cervix of women affected by cervical intraepithelial neoplasia grade 3 (CIN 3) with their smoking habits.

Materials And Methods: A total of 71 conization specimens of women affected by CIN 3 were separated in 3 groups according to their smoking habits (smokers, nonsmokers, and former smokers). The identification of the Langerhans cells was performed by immunohistochemical analysis using antibodies to S100 protein.

Langerhans' cells and smoking in intraepithelial neoplasia of the cervix.

Objective: To compare the intraepithelial population of Langerhans' cells (LC) in normal cervix epithelium adjacent to cervical intraepithelial neoplasia grade 3 (CIN 3) and correlate to smoking habit.

Methods: Cases in this study included conization specimens from 48 women affected by CIN 3. The LC count was performed in areas without histopathologic alteration adjacent to CIN 3.

Relationship of body fat distribution by waist circumference, dual-energy X-ray absorptiometry and ultrasonography to insulin resistance by homeostasis model assessment and lipid profile in obese and non-obese postmenopausal women.

Objective: To correlate body fat distribution evaluated by waist circumference, dual-energy X-ray absorptiometry and ultrasonography to insulin resistance and lipid profile in obese and non-obese postmenopausal women.

Methods: We studied 40 obese and 47 non-obese postmenopausal women, assessing obesity by measuring waist circumference and fat tissue using dual-energy X-ray absorptiometry and ultrasonography, and examining their correlation with metabolic parameters: insulin resistance as determined by the homeostasis model assessment technique (HOMA-IR) and lipid profile including triglycerides (TG), total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C), very-low-density lipoprotein, lipoprotein(a) (Lp(a)) and apoplipoprotein A-I (Apo A-I).

Results: There was no difference in lipid profile between the two groups.