Publications by authors named "Roberta Musa"
Comparison of Procalcitonin Assays on KRYPTOR and LIAISON XL Analyzers.
Diagnostics (Basel)
August 2019
Our laboratory performs procalcitonin (PCT) assays on a Brahms KRYPTOR analyzer with the Brahms PCT sensitive Kryptor kit. In this study, we wanted to compare the assays obtained in this way with the ones performed on the LIAISON XL. From January to May 2017, 171 samples were analyzed, of which 65 from female patients (age: 22-98 years) and 106 from male patients (age: 16-97 years).
View Article and Find Full Text PDFArticle Synopsis
- - The study focuses on determining sex-specific 99th percentile upper reference limits (URLs) for cardiac troponin I (cTnI) to improve accuracy in diagnosing acute myocardial infarction (AMI).
- - Blood samples from 300 males and 300 females were analyzed using two different high-sensitivity assays on the UniCel DxI 800 platform, revealing specific URLs of 5.5 ng/L for females and 13.9 ng/L for males for the Access hsTnI assay.
- - The researchers found that the Access hsTnI URLs were lower than the manufacturer's claims due to differences in population selection and sample types, leading them to suggest sticking with the manufacturer's original reference values.
Background The aims of this study were: (1) to calculate reliable thyroid stimulating hormone (TSH) reference intervals using laboratory databases; (2) to evaluate the relationship between TSH, sex and age values in different large Italian populations. Methods The TSH values stored in the laboratory information system of clinical laboratories of four Italian city hospitals, including 146,801 TSH measurements (with the respective age and sex data of individuals) were taken in consideration. Assuming a log-normal distribution, to log-transformed TSH values were applied the Dixon's iterative principle in order to exclude the outliers.
View Article and Find Full Text PDFBackground: Acute bacterial meningitis is a rare but extremely severe disease. The aim of this study was to investigate whether neutrophil gelatinase-associated lipocalin (NGAL) is present and measurable in cerebrospinal fluid (CSF) and if its assessment may be useful for identifying patients with bacterial meningitis.
Methods: Eligible specimens were all consecutive CSFs of patients with suspect acute bacterial meningitis that were referred from the Unit of Infectious Diseases for routine chemical and morphological analysis over a three months period.
Background: In vitro hemolysis can be induced by several biological and technical sources, and may be worsened by forced aspiration of blood in vacuum tubes. This study was aimed to compare the probability of hemolysis by drawing blood with a commercial evacuated blood collection tube, and S-Monovette used either in the "vacuum" or "aspiration" mode.
Materials And Methods: The study population consisted in 20 healthy volunteers.
Background: We planned a study to establish whether spurious hemolysis may be present in low volume tubes or partially filled tubes.
Methods: Four serum tubes were collected in sequence from 20 healthy volunteers, i.e.
Objectives: To assess the analytical performance of Beckman Coulter AU5800.
Design And Methods: Imprecision, linearity and comparison studies were performed on 12 routine clinical chemistry tests.
Results: Imprecision was comprised between 0.
Background: There is little information on temperature and period of freezing for generating hemolysate and blood cell lysate.
Materials And Methods: Primary tubes containing whole blood were frozen at -20°C and -80°C and then serially thawed to assess cell lysis and clinical chemistry tests in centrifuged plasma.
Results And Conclusions: Massive amount of blood cells lysis could only be obtained by storing samples 12h at -20°C, or 2h at -80°C.