Publications by authors named "Roberta Milazzo"

Article Synopsis
  • This study examines how laser surgery affects the maternal cardiovascular system in pregnancies with twin-twin transfusion syndrome, a condition that affects twins sharing a placenta.
  • Conducted from 2020 to 2022, it involved observing 42 affected pregnancies and comparing them with 15 healthier twin pregnancies, assessing various factors including blood chemistry and heart function before and after surgery.
  • The results show significant hemodynamic changes in the mothers post-surgery, with a survival rate of 72% for the affected twins and notable variations in blood pressure, heart rate, and overall cardiac performance.
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Background: Nutritional quality during pregnancy is crucial for mother and child health and their short/long-term outcomes. The aim of this study is to evaluate the adherence to nutritional recommendations in Italy during the three pregnancy trimesters in Normal Weight (NW) and Over Weight (OW) women.

Methods: Data from a multicenter randomized controlled trial included 176 women (NW = 133; OW = 43) with healthy singleton pregnancies enrolled within 13 + 6 weeks of gestation.

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Overweight and obesity during pregnancy have been associated with increased birth weight, childhood obesity, and noncommunicable diseases in the offspring, leading to a vicious transgenerational perpetuating of metabolic derangements. Key components in intrauterine developmental programming still remain to be identified. Obesity involves chronic low-grade systemic inflammation that, in addition to physiological adaptations to pregnancy, may potentially expand to the placental interface and lead to intrauterine derangements with a threshold effect.

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Anti-Ro/SSA antibodies are associated with a risk of 1-2 % to develop complete atrioventricular block (AVB) in fetuses of positive mothers. Complete AVB is irreversible, but studies suggest that anti-inflammatory treatment during the transition period from a normal fetal heart rate (FHR) to an AVB might stop this progression and restore sinus rhythm. The most efficient method for diagnostic evaluation of this arrhythmia is the pulsed-Doppler fetal echocardiography.

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