Inclusion of sevoflurane in cardioplegia reduces neutrophil activity during cardiopulmonary bypass.

Objective: The purpose of this study was to examine the effects of sevoflurane cardioplegia on neutrophil response and complement activation after cardiopulmonary bypass (CPB).

Design: A prospective, randomized clinical investigation.

Setting: University-affiliated hospital; single institutional.

Middle ear pressure changes after nitrous oxide anesthesia and its effect on postoperative nausea and vomiting.

Objectives/hypothesis: This study was designed to explore the relationship between changes in middle ear pressure associated with inhalational anesthesia and the incidence of postoperative nausea and vomiting (PONV).

Study Design: Prospective, randomized.

Methods: Middle ear compartment pressures were measured by tympanometry in 27 randomly assigned knee arthroscopy patients throughout the surgical procedure as well as into recovery.