Publications by authors named "Roberta Giorgi"
Article Synopsis
- MicroRNAs (miRNAs), such as hsa-miR-423-5p, play a significant role in regulating gene expression and are important for various biological processes, especially during pregnancy when maternal health impacts infant development.
- A longitudinal study conducted in southern Brazil examined the relationship between maternal levels of hsa-miR-423-5p in early pregnancy and cognitive development in infants at 90 days old, using blood samples and cognitive assessments.
- Results showed that higher maternal levels of miR-423-5p correlate with better cognitive abilities in infants, suggesting this miRNA could serve as a prenatal biomarker for predicting and potentially improving child neurocognitive development through early interventions.
Depression is a debilitating mental illness, one of the most prevalent worldwide. MicroRNAs have been studied to better understand the biological mechanisms that regulate this disease. This study review systematically the literature to identify which microRNAs are currently being associated with depression and their related pathways.
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