Publications by authors named "Roberta Gagliardi"
Background & Aims: Long-term albumin (LTA) is currently standard of care for patients with decompensated cirrhosis in many Italian hepatology centres. In this real-life study, we aimed to describe patient, logistical and treatment-related characteristics in daily clinical practice and to identify predictors of response.
Methods: We performed a multicentre, retrospective, observational study in patients with cirrhosis and ascites receiving LTA between 01/2016 and 02/2022 and followed until death, TIPS (transjugular intrahepatic portosystemic shunt) placement, transplantation or 02/2023.
Liver transplantation (LT) is the most successful treatment for patients with decompensated cirrhosis. The availability of effective and safe etiological treatments has altered the natural history of decompensated cirrhosis. Recently, the concept of recompensation has been defined.
View Article and Find Full Text PDFBackground & Aims: The prognostic impact of acute decompensation (AD), i.e. the development of complications that require hospitalization, has recently been assessed.
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- Bacterial infections before liver transplantation (LT) increase the risk of new infections and septic shock post-transplant but do not significantly affect long-term survival rates.
- A study at the Hospital of Padua analyzed 466 LT recipients from 2012 to 2018, finding that those with pre-LT infections had a higher incidence of complications after the surgery.
- Despite these complications, both 1-year and 5-year survival rates were similar between those with and without pre-LT infections, indicating the importance of timely transplants once infections resolve.
Background And Aims: Acute kidney injury (AKI) commonly occurs in patients with decompensated cirrhosis. Urinary neutrophil gelatinase-associated lipocalin (uNGAL) could help discriminate between different etiologies of AKI. The aim of this study was to investigate the use of uNGAL in (1) the differential diagnosis of AKI, (2) predicting the response to terlipressin and albumin in patients with hepatorenal syndrome-AKI (HRS-AKI), and (3) predicting in-hospital mortality in patients with AKI.
View Article and Find Full Text PDFendocarditis is a rare but dangerous disease. With this work, we intend to show the importance of early diagnosis and appropriate treatment in order to avoid complications. We also highlight the importance of local epidemiology to choose antibiotic prophylaxis for high-risk procedures in selected predisposed patients.
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