Incidence and status of insulin secretion in pregnant women with flat plasma glucose profiles during oral glucose tolerance test.

Objectives: Flat shaped glucose curves (FC) during oral glucose tolerance test (OGTT) in pregnant women (PW) are a not uncommon finding. We aimed to define the FC incidence in a large PW cohort and to describe the status of insulin and C-peptide secretion in women with FC when compared with a well-matched control group.

Methods: 1050 PW performing OGTT for gestational diabetes screening were enrolled.