Publications by authors named "Roberta Diehl Rodrigues"
Background: The association of moderate and severe dementia with low body mass index (BMI) is well described, but weight decline seems to also occur in individuals with preclinical neuropathologies. Considering that up to one-fifth of individuals with normal cognition meet the criteria for a dementia-related neuropathological diagnosis, autopsy studies are key to detecting preclinical neurodegenerative and cerebrovascular diseases that could be underlying weight changes.
Objective: We investigated the association between dementia-related brain lesions and BMI and evaluated whether the cognitive function was a mediator of this association.
Article Synopsis
- Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are adult-onset brain disorders related to abnormal tau protein deposition and categorized among atypical parkinsonian syndromes.
- This review summarizes recent findings on PSP and CBD, focusing on emerging clinical concepts, updated diagnostic criteria, and progress in identifying biomarkers.
- Advancements in research have expanded the understanding of PSP and CBD symptoms, leading to better diagnosis and recognition of various clinical manifestations and underlying pathology linked to these conditions.