Publications by authors named "Roberta Cappiello"
Background: Barrett's esophagus (BE) and esophagitis share potentially modifiable risk factors such as obesity, smoking, and alcohol. The role of diet on BE and esophagitis is still debated.
Aims: The objective of this study was to examine the association between some dietary habits and the risk of BE and esophagitis in Italy.
Knowledge about the association between alcohol and Barrett's oesophagus and reflux oesophagitis is conflicting. In this case-control study we evaluated the role of specific alcoholic beverages (red and white wine, beer and liquors) in 339 Barrett's oesophagus and 462 oesophagitis patients compared with 619 endoscopic controls with other disorders, recruited in twelve Italian endoscopic units. Data on alcohol and other individual characteristics were obtained from structured questionnaires.
View Article and Find Full Text PDFPurpose: To evaluate the role of smoking in Barrett's esophagus (BE) and erosive esophagitis (E) compared to endoscopic controls with no BE or E. Smoking is considered a cause of both BE and E, but results on this topic are quite controversial.
Methods: Patients with BE (339), E (462) and controls (619: 280 with GERD (gastroesophageal reflux disease)-negative and 339 with GERD-positive anamnesis) were recruited in 12 Italian endoscopy units.
History of cancer in first degree relatives of Barrett's esophagus patients: a case-control study.
Clin Res Hepatol Gastroenterol
December 2011
Article Synopsis
- - The study investigated the family history of cancer in patients with Barrett's esophagus (BE) and found that around 53% of BE patients had a relative with cancer, similar to esophagitis patients and controls.
- - Probands (patients) with relatives who had esophageal or gastric cancer were significantly more likely to have BE, with an 85% increased risk compared to those without affected relatives.
- - While no strong evidence linked family cancer history to BE diagnosis, the occurrence of early-onset E/G cancers in relatives suggests a potential genetic link, but larger studies are needed for clearer conclusions.
Aim: To compare two different daily doses of lansoprazole given for 12 weeks and to assess the role of gastrointestinal (GI) investigations as criteria for selecting patients.
Methods: Out of 45 patients referred for unexplained chronic persistent cough, 36 had at least one of the GI investigations (endoscopy, 24-h esophageal pH-metry and a 4-week trial of proton pump inhibitor (PPI) therapy) positive and were randomly assigned to receive either 30 mg lansoprazole o.d.