Trends in incidence, mortality, and survival for kidney cancer in Canada, 1986-2007.

Purpose: Kidney cancer is one of the fastest rising cancers worldwide. We aimed to examine the trends in incidence, mortality, and survival for this cancer in Canada.

Methods: Incidence data for kidney cancer for 1986-2010 were from the Canadian Cancer Registry and the National Cancer Incidence Reporting System.

Esophageal cancer in Canada: trends according to morphology and anatomical location.

Background: Esophageal adenocarcinoma has one of the fastest rising incidence rates and one of the lowest survival rates of any cancer type in the Western world. However, in many countries, trends in esophageal cancer differ according to tumour morphology and anatomical location. In Canada, incidence and survival trends for esophageal cancer subtypes are poorly known.

Short-term cancer mortality projections: a comparative study of prediction methods.

This paper provides a systematic comparison of cancer mortality and incidence projection methods used at major national health agencies. These methods include Poisson regression using an age-period-cohort model as well as a simple log-linear trend, a joinpoint technique, which accounts for sharp changes, autoregressive time series and state-space models. We assess and compare the reliability of these projection methods by using Canadian cancer mortality data for 12 cancer sites at both the national and regional levels.

Cancer and the environment: Ten topics in environmental cancer epidemiology in Canada.

This Chronic Diseases in Canada supplement is a compilation of literature reviews by scientific experts. It was initiated as follow-up to the Green Plan, the federal government's environmental agenda in the 1990s. In recognizing that Canadians are concerned about the environment and its relationship to their health, this document attempts to address some of these concerns in relation to cancer by reviewing and summarizing the epidemiological literature for ten environmental exposures, and highlighting future research needs.

Health outcomes of low-dose ionizing radiation exposure among medical workers: a cohort study of the Canadian national dose registry of radiation workers.

Background: Medical workers can be exposed to low-dose ionizing radiation from various sources. The potential cancer risks associated with ionizing radiation exposure have been derived from cohort studies of Japanese atomic bomb survivors who had experienced acute, high-level exposure. Since such extrapolations are subject to uncertainty, direct information is needed on the risk associated with chronic low-dose occupational exposure to ionizing radiation.

Adolescent injury deaths and hospitalization in Canada: magnitude and temporal trends (1979-2003).

Purpose: To understand the magnitude and the national trends of mortality and hospitalization due to injuries among Canadian adolescents aged 15-19 years in 1979-2003.

Methods: Data on injury deaths and hospitalizations were obtained from the national Vital Statistical System and the Hospital Morbidity Database. Injuries were classified by intent and by mechanism.

Decreases in occupational exposure to ionizing radiation among Canadian dental workers.

Objective: To describe doses of ionizing radiation and their possible associations with mortality rates and cancer incidence among Canadian dental workers.

Methods: The National Dose Registry (NDR) of Canada was used to assess occupational dose of ionizing radiation received by dental workers. The NDR cohort includes 42,175 people classified as dental workers.

Occupational exposure to chemical and petrochemical industries and bladder cancer risk in four western Canadian provinces.

Occupational factors have been proposed to play a critical role in bladder cancer. This population-based case-control study was conducted to confirm the association between selected occupational and non-occupational risk factors and risk of bladder cancer using data collected from the four western Canadian provinces. Unconditional logistic regression analyses were based on 549 histologically confirmed bladder cancer cases and 1099 controls.

Epidemiological study of Creutzfeldt-Jakob disease death certificates in Canada, 1979-2001.

Introduction: A descriptive epidemiological analysis to update trends of Creutzfeldt-Jakob disease (CJD) deaths, from 1979-2001, was undertaken.

Methods: Cases with CJD as underlying cause were extracted. Age-adjusted death rates by age, sex, and province were calculated.

Histology-related variation in the treatment and survival of patients with lung carcinoma in Canada.

Objectives: The aim of the study was to examine histologic differences in lung cancer treatment and survival, and to define recent survival trends in Ottawa, Canada.

Methods: From 1994 to 2000, 3,237 patients with invasive lung cancer were registered at the Ottawa Regional Cancer Centre (ORCC) and were followed up to 31 December 2001. Five-year relative survival rates (RSRs) and relative excess risks (RERs) of dying were calculated by stage and dominant initial treatment modalities for major cellular histologies using a relative survival model.

Increasing incidence of non-Hodgkin's lymphoma in Canada, 1970-1996: age-period-cohort analysis.

Previous studies have shown that the incidence of non-Hodgkin's lymphoma (NHL) has increased in many parts of the world in recent decades. Using data obtained from the Canadian Cancer Registry, the present study examined time trends in NHL incidence in Canada between 1970 and 1996 and the effects of age, period of diagnosis and birth cohort on incidence patterns for each sex separately. Results showed that overall age-adjusted incidence rates increased substantially, from 7.

An epidemiologic study of hepatocellular carcinoma in Canada.

Background And Methods: To provide information on poorly described Canadian hepatocellular cancer epidemiology, we analyzed incident cases abstracted from the Canadian Cancer Registration Database (1969-1997) and Canadian annual death data (1969-1998). Age, sex, geographic distribution, and secular trends were described. Projection models were developed for the next decade.

Trends in mortality and graft failure for renal transplant patients.

Background: Several important advances in general medical management both before and after renal transplantation have occurred over the last 5-15 years, however, few studies have formally examined trends in the outcomes of renal transplantation. We, therefore, aimed to determine the degree to which these advances have resulted in improved outcomes such as survival of patient and graft.

Methods: We analyzed the rates of death and graft failure among the 11,482 Canadians with end-stage renal disease who received a kidney transplant in 1981-98.