Publications by authors named "Robert Sciacca"

Article Synopsis
  • Transthyretin cardiac amyloidosis (ATTR-CA) leads to a higher incidence of arrhythmias, prompting a study to monitor patients for 2 weeks.
  • The study included 38 ATTR-CA patients and an age-matched control group, finding that 26.3% had atrial fibrillation/atrial flutter (AF/AFL) and a significant 81.6% had nonsustained ventricular tachycardia (NSVT).
  • Although ATTR-CA patients showed increased rates of these arrhythmias, there was no link between their presence and negative clinical outcomes over a median follow-up of 45 weeks, suggesting noninvasive monitoring may help in assessing arrhythmia risk.
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  • - The study evaluated the AF-HEART intervention, which uses mobile and telehealth technologies, to enhance patient management of atrial fibrillation (AF) through remote tracking and professional guidance on lifestyle factors.
  • - Over 6 months, 20 patients demonstrated significant outcomes, including a median of 181 heart rhythm recordings, an average weight loss of 3.5 kilograms, and improved quality-of-life scores.
  • - The findings suggest the AF-HEART intervention is feasible for continuous monitoring and improving patient outcomes, indicating potential for a larger randomized trial.
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  • A study analyzed intracardiac electrograms (EGMs) in 54 patients with atrial fibrillation (AF) to see how factors like BMI, age, and left atrial (LA) size affect EGM morphology.
  • The results indicated that higher BMI was linked to increased dominant frequency (DF) and mean spectral profile (MP), while older age and larger LA size were associated with decreased mean amplitude and width of the EGM.
  • These findings highlight how atrial remodeling due to these risk factors can lead to alterations in atrial activation patterns, potentially impacting the management and treatment of AF.
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  • * The ACTION study aimed to evaluate the feasibility of a mobile health intervention to enhance cardiac health management through nurse-led support, encouraging patients to set and track personal cardiac health goals.
  • * In a six-month pilot with 53 participants, mostly overweight and with common health issues, the program was well-received, with nearly all (98%) appreciating regular support from a dedicated nurse through an online platform.
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  • Patients with Tetralogy of Fallot (TOF) have a higher risk of sudden cardiac death and may receive implantable cardioverter defibrillators (ICDs) at a younger age.
  • A study of 44 TOF patients with ICDs found that 25% experienced inappropriate shocks, mostly due to atrial arrhythmias, with participants averaging 39 years at implantation.
  • Post-inappropriate shock treatments included adjusting the ICD settings and medications, highlighting the need for closer management of TOF patients with ICDs.
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  • * Out of 195 analyzed LVAD patients, 47% experienced significant VAs prior to the device implant, with 41% showing recurrent VAs post-implant during an average follow-up of 17 months.
  • * The presence of pre-LVAD AF significantly increased the risk of recurrent VAs (hazard ratio of 3.73), which were also linked to a higher mortality rate (hazard ratio of
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  • The study assessed how daily ECG self-recordings affect the detection and treatment timing of recurrent atrial fibrillation (AF) or atrial flutter (AFL) in patients undergoing specific treatments.
  • A total of 238 patients were divided into a control group receiving standard care and an intervention group using a mobile ECG device, revealing that the intervention group had a higher likelihood of detecting recurrence.
  • Results indicate that while mobile ECG devices facilitate earlier detection of AF/AFL recurrences, they also showed that control patients had a shorter time from detection to treatment.
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There are limited data on racial and ethnic disparities related to quality of life (QoL) and health literacy in adults with multiple cardiac conditions. This article evaluates the relationship between health literacy and QoL among patients with cardiac conditions in a multiethnic community in New York City.

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Background: Acute allograft rejection appears to be associated with increases in QT/QTc intervals.

Objectives: To determine the relationship between acute allograft rejection and electrocardiogram changes in patients undergoing an orthotopic heart transplant.

Methods: The study population comprised 220 adult patients undergoing heart transplant and enrolled in the NEW HEART study.

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  • The study investigates how mobile health (mHealth) technology compares to usual care in detecting and managing atrial fibrillation (AF) over 6 months.
  • Patients using daily smartphone ECG monitoring had a significantly higher detection rate of recurrent AF/AFL (61%) compared to controls (30%).
  • Improvements in quality of life were noted in physical functioning, vitality, and mental health among patients using mHealth, highlighting its effectiveness in patient self-management.
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  • The study aimed to find out how common atrial fibrillation (AF) is in patients with left ventricular assist devices (LVADs) and how it affects their cardiac health.
  • Researchers reviewed medical records of 249 patients at Columbia University Medical Center, discovering that 32% developed AF after getting an LVAD.
  • Interestingly, having AF did not significantly increase the risk of stroke or death, suggesting that while AF is prevalent in LVAD patients, it might not worsen their overall outcomes.
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Background: Atrial fibrillation is a major public health problem and is the most common cardiac arrhythmia, affecting an estimated 2.7 million Americans. The true prevalence of atrial fibrillation is likely underestimated because episodes are often sporadic; therefore, it is challenging to detect and record an occurrence in a "real world" setting.

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Background: Little attention has focused on gender differences in cardiac comorbidities and outcomes in patients undergoing orthotropic heart transplant.

Objective: The objective of this study was to investigate gender differences at baseline and during follow-up among heart transplant patients.

Methods: An observational cohort within the NEW HEART study was evaluated to determine gender differences in relation to age, coexisting cardiac comorbidities, and outcomes.

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Background: Although young women are presumed to have low cardiovascular disease (CVD) risk and mortality, the mortality benefits secondary to ischemic heart disease have plateaued among young women, <50 years.

Materials And Methods: Women, 18-49 years (n = 595) among all participants (n = 1,045) in the Columbia University Heart Health in Action Study, were assessed for CVD risk burden, that is, presence of hypertension, diabetes mellitus, current tobacco use, hyperlipidemia, physical inactivity, and/or obesity. Anthropometrics (height, weight, waist circumference, and body mass index [BMI]); demographics; socioeconomic status, CVD risk factors, body size perception; knowledge and awareness of CV disease; and attitudes toward lifestyle perception were determined.

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The impact of undergoing genetic testing in a Dominican population is not well understood. The objective of this investigation was to evaluate the psychological well-being and perceived cardiac risk among Dominicans who underwent genetic testing. Participants completed a qualitative interview and the Short Form-36 (SF-36) questionnaire after cardiac genetic testing.

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Background: Perception of body size is a key factor driving health behavior. Mothers directly influence children's nutritional and exercise behaviors. Mothers of ethnic minority groups and lower socioeconomic status are less likely to correctly identify young children as overweight or obese.

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Functional health literacy (FHL) has become an increasingly prevalent topic of discussion in patient health and well-being. Although FHL has been studied in a variety of populations, it has not been investigated in patients with pacemakers and implantable cardioverter defibrillators (ICDs).The purpose of this study was to evaluate FHL in a primarily older, urban-dwelling ICD/pacemaker population.

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Objective: To assess the effects of positive cardiac genetic diagnoses, ICD discharges, and arrhythmias on measures of psychological well-being.

Methods: Fifty-eight adults with prior cardiac genetic testing were enrolled. Patient well-being was determined using the SF-36 (QoL), HADS-A and HADS-D (anxiety/depression), and IPQ-R (patients' perceptions of illness).

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Background: While knowledge of cardiovascular disease (CVD) has improved, it remains low among minority women, thereby contributing to disparities and posing health challenges. Moreover, substantial numbers of women do not recognize that excess weight imposes CVD risk and increases morbidity and decreases survival. In order to test the hypothesis that CVD knowledge is reduced among overweight and obese women, CVD knowledge and weight perception was compared among Hispanic and non-Hispanic white (NHW) women.

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Background: It is not known whether cardiovascular disease (CVD) risk level is related to knowledge of the leading cause of death of women or heart attack symptoms.

Hypothesis: Women with higher CVD risk estimated by Framingham Risk Score (FRS) or metabolic syndrome (MS) have lower CVD knowledge.

Methods: Women visiting primary care clinics completed a standardized behavioral risk questionnaire.

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Aims And Objectives: To determine the relationship between quality of life and perceived self-reported symptoms in an older, ambulatory, urban population living with heart failure.

Background: While arrhythmias in older individuals with heart failure are well documented, the association between perceived arrhythmia symptoms and quality of life is not well-defined.

Design: Prospective, cross-sectional single-centre study.

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The purpose of this study was to describe the clinical, research, educational, and professional activities that nurses are engaged in following participation in a 2 month intramural genetics training program. An online survey was administered in 2010 to graduates of the program sponsored by the US National Institute of Nursing Research from 2000 to 2009, in Bethesda, Maryland, USA. The electronic, voluntary survey was sent to 189 graduates via email.

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Background: Inadequate cardiovascular disease (CVD) knowledge has been cited to account for the imperfect decline in CVD among women over the last 2 decades.

Hypothesis: Due to concerns that at-risk women might not know the leading cause of death or symptoms of a heart attack, our goal was to assess the relationship between CVD knowledge race/ethnicity, education, and body mass index (BMI).

Methods: Using a structured questionnaire, CVD knowledge, socio-demographics, risk factors, and BMI were evaluated in 681 women.

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Unlabelled: Abstract Background: The diversity of the U.S. population and disparities in the burden of cardiovascular disease (CVD) require that public health education strategies must target women and racial/ethnic minority groups to reduce their CVD risk factors, particularly in high-risk communities, such as women with the metabolic syndrome (MS).

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Atrial and ventriclar tachyarrhythmias, as well as bradyarrhythmias, in the elderly with heart failure (HF) and/or hypertension (HTN) have been well documented. However, the frequency of these arrhythmias, whether silent or symptomatic, and their association with subsequent cardiac events has not been well defi ned in patients 65 years or older with HF and other cardiovascular risk factors. To assess the value of 2 weeks of remote, transtelephonic cardiac monitoring for detecting arrhythmias in an elderly, urban population living with HF.

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