Periodontal regeneration - furcation defects: a consensus report from the AAP Regeneration Workshop.

Background: Treatment of furcation defects is a core component of periodontal therapy. The goal of this consensus report is to critically appraise the evidence and to subsequently present interpretive conclusions regarding the effectiveness of regenerative therapy for the treatment of furcation defects and recommendations for future research in this area.

Methods: A systematic review was conducted before the consensus meeting.

Periodontal Regeneration - Furcation Defects: Practical Applications From the AAP Regeneration Workshop.

Focused Clinical Question: How should periodontal furcation defects be managed via periodontal regenerative therapy, and what parameters should be used for treatment selection? Summary: The treatment of furcation defects can vary based on the type and location of the furcation involvement. Attaining predictable regenerative outcomes is dependent on the control of local and systemic factors. A combined treatment approach (barrier and bone replacement graft with or without biologic) generally offers the better therapeutic outcome over monotherapy.

Local minocycline as an adjunct to surgical therapy in moderate to severe, chronic periodontitis.

Objective: The aim of the study was to evaluate the effects of minocycline microspheres on periodontal probing depth reduction when used in combination with surgery in adults with moderate to severe, chronic periodontitis.

Material And Methods: Sixty patients with a minimum of one non-molar periodontal site > or =6 mm in two oral quadrants received either local minocycline microspheres at baseline, immediately following each of two surgical therapies (Weeks 2 and 3), and at Week 5 or surgery alone.

Results: The mean probing depth reduction at Week 25 at sites > or =5 mm at baseline was 2.

Factors influencing the outcome of regenerative therapy in mandibular Class II furcations: Part I.

Background: Factors influencing the outcome of regenerative therapy of Class II furcations are incompletely and poorly understood. The purpose of this 24-month prospective study was to examine the relationship of patient-, site-, and treatment-related factors to the clinical closure of randomly selected mandibular Class II furcations. Results of therapy were evaluated at 1 and 2 years postoperatively.