Evaluation of the microbial flora found in woodwind and brass instruments and their potential to transmit diseases.

Previous studies of dental devices (toothbrushes, dentures, and protective athletic mouthguards) have demonstrated microbial contamination of these devices and possible transmission of infectious diseases to the users. Since woodwind and brass instruments come into intimate contact with the musician's oral cavity and often are passed from student to student without sanitization, the question arises as to whether these instruments are contaminated and can transmit microbial diseases. The purpose of this study was to determine if woodwind and brass instruments and/or their cases harbor opportunistic, pathogenic, or allergenic microorganisms that can be transmitted to the musician.

Evaluation of cleansing methods for previously worn prostheses.

Statement Of Problem: Although there are many product claims that address the issue of denture sanitization, controlled scientific studies on previously worn dentures have not been performed.

Purpose: The purpose of this study was to evaluate procedures directed at sanitizing previously worn contaminated dentures from two regions of the United States.

Materials And Methods: This study examined 51 previously worn dentures from two regions.

Microbiota found in protective athletic mouthguards.

Background: Protective athletic mouthguards (PAM) produce oral mucosal injuries and may be associated with other systemic conditions.

Hypothesis: With wear, PAM become contaminated by a range of microorganisms. The number of microorganisms in PAM can be reduced by daily use of an antimicrobial solution.

Status of bacterial colonization, Toll-like receptor expression and nuclear factor-kappa B activation in normal and diseased human livers.

Epidemiological data on bacterial translocation (BT), colonization and inflammation in normal human livers is lacking. In this study we investigated the status of bacterial colonization and inflammation in the normal, cirrhotic primary biliary cirrhosis (PBC), and nonalcoholic steatohepatitis (NASH) human liver tissues. Comparatively normal livers showed increased bacterial colonization than PBC and NASH.

Triclosan-induced modification of unsaturated fatty acid metabolism and growth in Pseudomonas aeruginosa PAO1.

Triclosan is a broad-spectrum antimicrobial agent having low toxicity which facilitates its incorporation into numerous personal and health care products. Although triclosan acts against a wide range of gram-positive and gram-negative bacteria by affecting fatty acid biosynthesis, it is ineffective against the opportunistic pathogen Pseudomonas aeruginosa. Wild-type strain P.

Evaluation of microbial flora found in previously worn prostheses from the Northeast and Southwest regions of the United States.

Statement Of Problem: Denture-induced stomatitis is a recognized clinical challenge. The responsible microorganisms have not been delineated and may differ among regions of the United States.

Purpose: The purpose of this study was to identify the microorganisms found in dentures from 2 geographic regions.

Protective athletic mouthguards: do they cause harm?

Background: Protective athletic mouthguards (PAMs) have been worn in competitive sports for more than 100 years. Today, participants in contact and noncontact sports wear PAMs.

Hypothesis: Wearing a PAM produces oral injury.

Possible disease transmission by contaminated mouthguards in two young football players.

Previous studies have demonstrated that athletic mouthguards worn by ice hockey and football players harbor large numbers of bacteria, yeasts, and molds, some of which are either opportunistic or frank pathogens. This article details the clinical history of two junior high school football players. The first player had cellulitis of the leg after a non-break injury.

Effect of outer membrane permeabilisation on intrinsic resistance to low triclosan levels in Pseudomonas aeruginosa.

The present study was undertaken to investigate the possibility that outer cell envelope impermeability might be involved in the intrinsic resistance of Pseudomonas aeruginosa to low levels of the hydrophobic biocide triclosan. Macrobroth dilution and batch cultural turbidimetric assays were employed to assess the ability of compounds that render the Gram-negative outer membrane permeable to non-polar molecules to sensitise cell envelope variants to triclosan. Pseudomonas aeruginosa strains possessing highly refractory (PAO1) and atypically permeable (Z61) outer cell envelopes as well as a PAO1 derivative lacking four multidrug efflux pumps (YM64) were examined.

Evaluation of the sanitization effectiveness of a denture-cleaning product on dentures contaminated with known microbial flora. An in vitro study.

Objectives: To see if dentures contaminated with Staphylococcus aureus, Pseudomas aeruginosa, Bacillus cereus, Candida albicans, and herpes simplex virus 1 could be effectively decontaminated by using Medical Tabs for Dentures.

Method And Materials: Ten methylmethacrylate dentures with processed soft liners (soft-liner dentures) and 10 methylmethacrylate dentures without processed soft liners (hard dentures) were aseptically fragmented and individually incubated with a target microorganism. Test denture fragments were immersed in Medical for 5 minutes, vortexed for 5 minutes, and serially diluted onto media.

A statistical comparison of denture sanitation using a commercially available denture cleaner with and without microwaving.

Polymethyl-methacrylate dentures, worn by patients for periods ranging from 12 days to 48 years, were cultured and found to be heavily contaminated with a variety of microorganisms both externally and internally. A commercially available denture sanitizer, used as prescribed by the manufacturer, was ineffective at decontaminating the dentures. This study examined the effectiveness of this denture sanitizer when used in combination with a microwaving procedure.