Acutoxbase, an innovative database for in vitro acute toxicity studies.

Acutoxbase is as an internet-based database developed for coherent management of all information relevant to the EU integrated project 'A-Cute-Tox' (www.acutetox.org), which aims to optimise and prevalidate an in vitro testing strategy for predicting acute human toxicity.

Electrocardiographic features and prognosis in acute diagonal or marginal branch occlusion.

The aim of our study was to analyze electrocadiographic changes in patients with acute myocardial infarction related to the occlusion of diagonal (DG) or marginal (MG) branch. We selected 13 cases with DG and 12 with MG occlusion on angiography and evaluated their electrocardiogram (ECG) patterns on admission obtained in emergency department (ED) of university hospital with catheterization laboratory serving everyday interventional cardiology duty for ACS. Most characteristic ECG changes in acute occlusion of DG observed in 12 patients (92.

Prognostic implications of myocardial necrosis triad markers' concentration measured at admission in patients with suspected acute coronary syndrome.

The aim of the study was to analyze the prognostic implications of 3 myocardial necrosis markers measured at admission in short-term observation of patients with suspected acute coronary syndrome. The study group consisted of 336 consecutive patients whose concentration of cardiac troponin I, creatine kinase-MB fraction, and myoglobin were measured at admission. All patients referred due to chest pain and suspected acute coronary syndrome and were followed up for 30 days.

Previously undiagnosed congenitally corrected transposition of the great arteries in a 51-year-old woman with chronic heart failure symptoms.

We describe the case of a 51-year-old female with previously undiagnosed congenitally corrected transposition of the great arteries (ccTGA) who was admitted to the hospital due to the exacerbated symptoms of heart failure for planned coronary angiography. Patient cardiac functional status appeared to have gradually regressed to New York Heart Association class III at the time of the admission. The chart reviews were performed.

Admission B-type natriuretic peptide assessment improves early risk stratification by Killip classes and TIMI risk score in patients with acute ST elevation myocardial infarction treated with primary angioplasty.

Background: TIMI risk score for ST elevation acute myocardial infarction (STEMI) and Killip classes are simple tools for early risk stratification.

Aim: This study aims to evaluate the hypothesis that admission of BNP adds prognostic information to Killip classes and TIMI risk score in patients with STEMI treated with primary percutaneous coronary intervention (PCI).

Methods: BNP concentrations in blood samples obtained on admission in 126 consecutive patients (mean age 58.

Prognostic value of B-type natriuretic peptide levels on admission in patients with acute ST elevation myocardial infarction.

Objective: To assess the relation between B-type natriuretic peptide (BNP) levels on admission in ST elevation myocardial infarction (STEMI) and short-term, all-cause mortality.

Methods And Results: Blood samples for BNP determination were obtained on admission in 88 patients (mean age 60.6 +/- 10.

Diagnostic value of BNP in suspected perimyocarditis--a preliminary report.

Background: Diagnosis of perimyocarditis is often very challenging. Clinical presentation includes chest pain and ECG changes which are difficult to interpret. Clinical course is usually mild, however, some patients develop heart failure symptoms and require aggressive treatment.

The simulation of emergency cases and other computer-based learning programs on the Internet for medical students and young doctors.

The aim of the project was to evaluate several of the most interesting Intemet "interactive patient" programs, as well as simulations of real clinical cases, and to compare them with a program "The Simulation of Emergency Cases" described in this work, and created by the Students' Research Group at the Department of Medical Informatics, the Medical University of Warsaw. These programs are aimed at medical students and doctors, and they are of great help in gaining medical experience in situations when the access to the real patient is limited.

Serum B-type natriuretic peptide levels on admission predict not only short-term death but also angiographic success of procedure in patients with acute ST-elevation myocardial infarction treated with primary angioplasty.

Background: B-type natriuretic peptide (BNP) levels are predictive of short-term death in patients with acute coronary syndromes. Few data are available for BNP levels obtained on admission in patients with acute ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI).

Methods: Blood samples for BNP estimation, obtained on admission in 126 consecutive patients (mean age, 58.

Telemedicine in the context of different medical specialities. The Polish perspective.

Unlabelled: Two types of telemedicine are considered in the paper: pre-recorded and real-time. The advantages and disadvantages of each type are described.The choice of telemedicine type depends on medical speciality.

Project of an expert system supporting risk stratification and therapeutic decision making in acute coronary syndromes.

The aim of the project was to create a computer program--expert system, which will support a doctor when a management for patients with acute coronary syndrome needs to be chosen. The expert system consists of four modules: knowledge base, previous cases database, inference engine and explanation module. Knowledge base was created with support of clinical experts, based on current management standards, guidelines and results of clinical trials according to evidence-based medicine rules.