Transforming safety culture in neonatal intensive care teams.

Background: Healthcare organisations face widespread challenges in optimising their safety culture, especially amid conflicting stakeholder needs, staffing shortages and increasing acuity of patients. McMaster University Children's Hospital Neonatal Intensive Care Unit developed a safety culture programme that prioritises the needs of patients, hospital staff and learners altogether.

Methods: The safety culture programme and activities revolve around six primary drivers: psychological safety, provider well-being, equity, diversity and inclusion, teamwork and communication, organisational learning and leadership.

Semi-empirical analysis of leptons in gases in crossed electric and magnetic fields. Part II. Transverse compression of muon beams.

This article employs fluid equations to analyze muon beams in gases subject to crossed electric and magnetic fields, focusing, in particular, on a scheme proposed by Taqqu [Phys. Rev. Lett.

Semi-empirical analysis of leptons in gases in crossed electric and magnetic fields. I. Electrons in helium.

In this series, we outline a strategy for analyzing electrons and muons in gases in crossed electric and magnetic fields using the straightforward transport equations of momentum-transfer theory, plus empirical arguments. The method, which can be carried through from first principles to provide numerical estimates of quantities of experimental interest, offers a straightforward, physically transparent alternative to "off-the-shelf" simulation packages, such as Magboltz and GEANT. In this first article, we show how swarm data for electrons in helium gas subject to an electric field only can be incorporated into the analysis to generate electron swarm properties in helium gas in crossed electric and magnetic fields and to estimate the Lorentz angle in particular.

Legal Privilege Legislation: Consequences for Patient Safety.

Increasing awareness of the extent of preventable harm from healthcare has led to efforts to improve patient safety through a variety of efforts, including legislation. Extending legal privilege to quality and safety reviews leads to further harm for many patients, families and healthcare providers. The intentional isolation, silencing and exclusion after the incident undermines trust, prevents learning and impedes an opportunity to heal and recover for all those directly involved.

Commentary: Three Ideas about "Post-Vention".

When presented with the opportunity to provide a commentary on this Special Issue of Healthcare Quarterly on patient safety, we thought it would be particularly powerful to bring together those with intimate lived experience of patient safety incidents. As such, this submission is being brought to you by two patients whose lives have been irrevocably altered by medical mishaps, along with a physician who has spent a considerable portion of his career advancing and integrating the patient voice on patient safety issues.

Cohort profile: prescriptions dispensed in the community linked to the national cancer registry in England.

Purpose: The linked prescriptions cancer registry data resource was set up to extend our understanding of the pathway for patients with cancer past secondary care into the community, to ultimately improve patient outcomes.

Participants: The linked prescriptions cancer registry data resource is currently available for April to July 2015, for all patients diagnosed with cancer in England with a dispensed prescription in that time frame.The dispensed prescriptions data are collected by National Health Service (NHS) Prescription Services, and the cancer registry data are processed by Public Health England.

Azotobacter Genomes: The Genome of Azotobacter chroococcum NCIMB 8003 (ATCC 4412).

The genome of the soil-dwelling heterotrophic N2-fixing Gram-negative bacterium Azotobacter chroococcum NCIMB 8003 (ATCC 4412) (Ac-8003) has been determined. It consists of 7 circular replicons totalling 5,192,291 bp comprising a circular chromosome of 4,591,803 bp and six plasmids pAcX50a, b, c, d, e, f of 10,435 bp, 13,852, 62,783, 69,713, 132,724, and 311,724 bp respectively. The chromosome has a G+C content of 66.

Housing conditions in 2 Canadian First Nations communities.

Objectives: Housing conditions were assessed in 2 Canadian First Nations communities. Possible associations with tuberculosis (TB) were explored. Study design.

Exchangeability of mammalian DNA ligases between base excision repair pathways.

In mammalian cells, DNA ligase IIIalpha and DNA ligase I participate in the short- and long-patch base excision repair pathways, respectively. Using an in vitro repair assay employing DNA ligase-depleted cell extracts and DNA substrates containing a single lesion repaired either through short-patch (regular abasic site) or long-patch (reduced abasic site) base excision repair pathways, we addressed the question whether DNA ligases are specific to each pathway or if they are exchangeable. We find that immunodepletion of DNA ligase I did not affect the short-patch repair pathway but blocked long-patch repair, suggesting that DNA ligase IIIalpha is not able to substitute DNA ligase I during long-patch repair.

Reversible phase variation in the phnE gene, which is required for phosphonate metabolism in Escherichia coli K-12.

It is known that Escherichia coli K-12 is cryptic (Phn-) for utilization of methyl phosphonate (MePn) and that Phn+ variants can be selected for growth on MePn as the sole P source. Variants arise from deletion via a possible slip strand mechanism of one of three direct 8-bp repeat sequences in phnE, which restores function to a component of a putative ABC type transporter. Here we show that Phn+ variants are present at the surprisingly high frequency of >10(-2) in K-12 strains.

The structure and mechanism of serine acetyltransferase from Escherichia coli.

Serine acetyltransferase (SAT) catalyzes the first step of cysteine synthesis in microorganisms and higher plants. Here we present the 2.2 A crystal structure of SAT from Escherichia coli, which is a dimer of trimers, in complex with cysteine.