Publications by authors named "Robert Pugatch"

Article Synopsis
  • - The study aimed to assess if model-based iterative reconstruction (MBIR) enhances diagnostic confidence and detection rates of pulmonary embolism (PE) during computed tomography pulmonary angiography, compared to hybrid iterative reconstruction (HIR) and filtered back projection (FBP) techniques.
  • - Fifty patients were evaluated, with each study reconstructed using FBP, HIR, and MBIR, and assessed by radiologists on various criteria, including diagnostic confidence and detection of PE, with results showing MBIR significantly improved PE detection and confidence levels compared to FBP and HIR.
  • - The study found that while accuracy rates were similar across the three methods, MBIR had a notably higher sensitivity for detecting PE, as well as subjective improvements in image
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Article Synopsis
  • - Pulmonary alveolar proteinosis (PAP) can occur in a primary idiopathic form, primarily affecting middle-aged individuals, or due to factors like inhalation exposure, blood cancers, or immune issues, with tobacco use being a significant risk factor.
  • - Symptoms of PAP can range from mild breathlessness to severe respiratory failure, and a characteristic "crazy-paving" pattern is seen on CT scans, distinguishing it from other lung conditions.
  • - Diagnosis typically involves lung biopsy or bronchoalveolar lavage to find specific protein deposits, and while whole-lung lavage helps with symptoms, new therapies targeting immune deficiencies show moderate effectiveness.
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Rationale And Objectives: The purpose of this multicenter, multireader study was to evaluate the performance of computed tomography (CT) lung nodule computer-aided detection (CAD) software as a second reader.

Methods And Materials: The study involved 109 patients from four sites. The data were collected from a variety of multidetector CT scanners and had different scan parameters.

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Pleuropulmonary synovial sarcoma (PPSS) is increasingly recognized as a subtype of sarcoma because of the recent identification of a distinctive chromosomal translocation specific to synovial sarcoma. Soft-tissue synovial sarcoma is far more common than PPSS and typically develops in para-articular locations of the extremities; affects young and middle-aged adults, with no difference in distribution between the sexes; and has well-documented radiologic manifestations. PPSS may arise in the chest wall, heart, mediastinum, pleura, or lung, and it shares patient demographics and several imaging features with its soft-tissue counterpart.

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Imaging plays an integral role in diagnosing, staging, and following patients with lung cancer. Many lung neoplasms are detected on chest radiographs, but the majority of patients have advanced stage disease at the time of presentation. There is a wide spectrum of radiologic manifestations of lung cancer, and recognition of these findings is essential for patient management.

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Lymphangioleiomyomatosis (LAM) is an uncommon interstitial lung disease that exclusively affects women, usually during their reproductive years. LAM is characterized pathologically by abnormal proliferation of LAM cells in the lungs and in thoracic and retroperitoneal lymphatics. Thirty-three cases of LAM were reviewed retrospectively for clinical and radiologic findings.

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