Publications by authors named "Robert Pooley"

Sinusoidal large B-cell lymphoma (SLBCL) is a rare morphologic variant of diffuse large B-cell lymphoma that is associated with poor outcomes. The diagnosis of SLBCL may be challenging due to its unique morphologic features on cytologic preparation and histologic section. This case report describes the incidental diagnosis of SLBCL with a focus on comparative cyto-histologic findings.

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Purpose: Cartilage cap resurfacing is a method to seal a superior semicircular canal dehiscence. The purpose of this study was to evaluate the detection of new bone formation after surgical placement of a cartilage cap over a dehiscent semicircular canal.

Methods: In this retrospective review, two neuroradiologists blinded to each other's interpretation reviewed the temporal bones of 20 patients, five of which had a pre-operative computed tomography (CT) exam which was interpreted as unilateral superior semicircular canal dehiscence and with new bone formation following repair on follow-up CT.

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Background: Using ultrasound to measure optic nerve sheath diameter (ONSD) is an emerging bedside technique to noninvasively assess intracranial pressure (ICP) in patients with brain injury. This technique is unique among bedside ultrasonography and is often performed by providers who have no formal ultrasound training. We sought to create a low-cost, 3D, reusable ONSD model to train neurology, neurosurgery, and critical care providers in measuring ICP.

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Article Synopsis
  • Cardiac myxomas are the most common primary tumors of the heart, with atypical locations posing higher surgical risks.
  • A case of a 63-year-old woman with a cardiac myxoma in an unusual position was treated using three-dimensional printing to assist in surgical planning.
  • The tumor was successfully removed, and while the patient developed sick sinus syndrome post-surgery, there was no tumor recurrence after one year, highlighting the benefits of 3D printing technology in such cases.
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Background: To our knowledge, this is the first time that a three-dimensional (3D)-printed model was used as an intraoperative template to recreate the resected portion of the lateral chest wall after resection of a large chest-wall tumour.

Methods: Fabrication of 3D-printed models requires collaboration among a surgeon, radiologist, segmenter, and 3D printing centre. Three-dimensional models are created with computed tomographic and magnetic resonance data.

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Article Synopsis
  • The study examines the safety and image quality of 1.5-T multiparametric MRI for prostate imaging in patients with cardiac implantable electronic devices (CIEDs) compared to patients without CIEDs.
  • No serious adverse effects were reported in patients with CIEDs, with the specific absorption rate (SAR) remaining below 1.5 W/kg, but signal-to-noise ratio (SNR) was slightly lower than in controls.
  • Overall image quality ratings were similar between the CIED group and the control group, indicating that MRI can be performed safely in this patient population under controlled settings.
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The purpose of this work was to investigate the performance of currently available magnetic resonance imaging (MRI) for detecting kidney stones, compared to computed tomography (CT) results, and to determine the characteristics of successfully detected stones. Patients who had undergone both abdominal/pelvic CT and MRI exams within 30 days were studied. The images were reviewed by two expert radiologists blinded to the patients' respective radiological diagnoses.

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Background And Purpose: With the development of ultrashort echo time (UTE) sequences, it may now be possible to detect kidney stones by using magnetic resonance imaging (MRI). In this study, kidney stones of varying composition and sizes were imaged using both UTE MRI as well as the reference standard of computed tomography (CT), with different surrounding materials and scan setups.

Methods: One hundred and fourteen kidney stones were inserted into agarose and urine phantoms and imaged both on a dual-energy CT (DECT) scanner using a standard renal stone imaging protocol and on an MRI scanner using the UTE sequence with both head and body surface coils.

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Background & Aims: Increasingly, pancreatic cysts are discovered incidentally in patients undergoing cross-sectional imaging for nonpancreatic reasons. It is unclear whether this increase is caused by improved detection by progressively more sophisticated cross-sectional imaging techniques or by a true increase in prevalence. We aimed to determine the prevalence of incidental pancreatic cysts in patients undergoing magnetic resonance imaging (MRI) for nonpancreatic indications on successive, increasingly sophisticated MRI systems.

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Purpose: Dual-energy computed tomography (DECT) has shown the capability of differentiating uric acid (UA) from non-UA stones with 90-100% accuracy. With the invention of dual-source (DS) scanners, both low- and high-energy images are acquired simultaneously. However, DECT can also be performed by sequential acquisition of both images on single-source (SS) scanners.

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Computed tomography (CT) is the current gold standard for imaging kidney stones, albeit at the cost of radiation exposure. Conventional magnetic resonance imaging (MRI) sequences are insensitive to detecting the stones because of their appearance as a signal void. With the development of 2D ultra-short echo-time (UTE) MRI sequences, it becomes possible to image kidney stones in vitro.

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Introduction: The management of EEG patterns in comatose intensive care unit patients remains poorly studied regarding whether aggressive management improves outcomes. We hypothesized that stimulus-induced rhythmic, periodic, or ictal discharges (SIRPIDs) could be classified as ictal and interictal using single-photon emission computerized tomographic (SPECT) imaging to help guide aggressive or deescalate anticonvulsant management.

Methods: We performed a retrospective review of all cases of ICU patients at a single center, tertiary care academic center for evidence of SIRPIDs with concomitant SPECT imaging over a one year period.

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Object: Near-infrared spectroscopy (NIRS) offers noninvasive bedside measurement of direct regional cerebral arteriovenous (mixed) brain oxygenation. To validate the accuracy of this monitoring technique, the authors analyzed the statistical correlation of NIRS and CT perfusion with respect to regional cerebral blood flow (CBF) measurements.

Methods: The authors retrospectively reviewed all cases in which NIRS measurements were obtained at a single, academic neurointensive care unit from February 2008 to June 2011 in which CT perfusion was performed at the same time as NIRS data was collected.

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Article Synopsis
  • Endoscopic clipping devices used for GI treatments are generally labeled as MRI incompatible, but this study aims to evaluate their actual performance in an MRI environment.
  • Using excised pig tissue, the research tested various endoclips (Resolution Clip, TriClip, QuickClip, and Ethicon Endo-surgery Clip) in a 1.5-Tesla MRI scanner, focusing on their physical deflection and detachment.
  • Results indicated that only the Ethicon Endo-surgery clip showed compatibility with MRI, while the TriClip was the only one to detach from the tissue, suggesting it is incompatible with MRI.
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Background: To enhance the sensitivity and specificity of the clinical diagnosis of progressive supranuclear palsy (PSP), neuroradiological parameters established in pathologically proven cases are needed.

Methods: We examined brainstem atrophy in five pathologically confirmed PSP patients (three men, mean age at death 77 years, range 64-84 years). Time interval between symptom onset and MRI ranged from 1 to 5 years, and between MRI and death from 33 to 52 months.

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Objective: Transient interruption of the contrast bolus has been described as a physiologic artifact that can sometimes result in poor opacification of the pulmonary arteries on pulmonary CT angiographic studies. To better understand the mechanism underlying this artifact, we used velocity-encoded cine MRI to measure flow in the inferior vena cava (IVC) and superior vena cava (SVC) during respiratory maneuvers.

Subjects And Methods: Quantitative measurements of SVC and IVC flow per R-R interval were performed on 10 healthy volunteers (six men, four women; median age, 30 years; range, 25-55 years) with a retrospectively ECG-gated velocity-encoded gradient-echo cine sequence on a 1.

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The objective of this clinical-pathologic study was to identify biomarkers for a pallidopontonigral degeneration (PPND) kindred of frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) harboring the N279K tau mutation. Five affected subjects, one at-risk who later became symptomatic, and one at-risk asymptomatic mutation carrier, had abnormal (18)fluorodeoxyglucose PET demonstrating asymmetric temporal lobe hypometabolism. All except the asymptomatic mutation carrier had abnormal brain MRI.

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Learning the basic concepts required to understand magnetic resonance (MR) imaging is a straightforward process. Although the individual concepts are simple, there are many concepts to learn and retain simultaneously; this situation may give the illusion that learning the physics of MR imaging is complicated. It is important for the radiologist who interprets MR images to understand the methods used to create the images because image contrast specifically depends on how the image data were acquired.

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Objective: To determine whether cranial magnetic resonance imaging (MRI) is associated with deep brain stimulation (DBS) lead displacement or program interference.

Methods: In vitro and in vivo studies were performed with the Itrel II implantable pulse generator (IPG) (Model 7424; Medtronic, Minneapolis, MN), Medtronic 3387 and 3389 leads, and a 1.5-T GE Horizon LX scanner (General Electric, Milwaukee, WI).

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