Publications by authors named "Robert Molinari"

Study Design: Retrospective cohort study.

Objectives: Atypical hangman's fractures are associated with increased risk for neurologic injury due to involvement of the posterior cortex of the axis body. We present the largest single-center cohort of atypical hangman's fractures with the goal of guiding treatment decisions and outcomes based on fracture classification.

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Background: Several assessment tools have been developed to estimate a patient's likelihood risk of falling. None of these measures estimate the contributions of the visual, vestibular, and somatosensory systems to fall risk, especially in patients with degenerative lumbar spine disease.

Methods: Degenerative lumbar spine patients with radiculopathy (LD) and healthy subjects who were 35-70 years old without spine complaints were recruited.

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Study Design: Retrospective review of a single institution cohort.

Objective: To determine whether area deprivation index (ADI) or social vulnerability index (SVI) is more suitable for evaluating minimum clinically important difference (MCID) achievement following elective lumbar fusion as captured by the Patient-Reported Outcomes Measurement Information System (PROMIS).

Summary Of Background Data: A total of 182 patients who underwent elective one-level to two-level posterior lumbar fusion between January 2015 and September 2021.

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Article Synopsis
  • The study aimed to evaluate how different states of depression affect postoperative outcomes measured by PROMIS scores in patients undergoing lumbar fusion surgery.
  • Using a sample of 200 patients, researchers categorized them into nondepressed, clinically depressed, and situationally depressed based on their depression scores and diagnoses.
  • While all patient groups showed improvement post-surgery, situationally depressed individuals had worse preoperative physical function and were more likely to meet the minimum clinically important difference (MCID) for physical function improvement, although there was no significant difference for pain interference outcomes.
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Introduction: Historically musculoskeletal injury has substantially affected United States (US) service members. Lumbosacral spine injuries are among the most common sites of injury for service members across all US military branches and usually presents with pain in the lower back and extremities. The aim of this study is to identify and describe the 50 most-cited articles relevant to military medicine on the subject of the spine.

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Background Context: Socioeconomic status (SES) has been associated with differential healthcare outcomes and may be proxied using the area-deprivation index (ADI). Few studies to date have investigated the role of ADI on patient-reported outcomes and clinically meaningful improvement following lumbar spine fusion surgery.

Purpose: The purpose of this study is to investigate the role of SES on lumbar fusion outcomes using Patient-Reported Outcomes Measurement Information System (PROMIS) surveys.

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Background: Spinal injuries, whether mechanical or neurological, frequently require urgent intervention. Superior outcomes are associated with earlier intervention, which often requires operating overnight and on weekends. However, operating after hours has been associated with increased risks of complications in selected studies.

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Study Design: Retrospective review of a single institution cohort.

Objective: The goal of this study is to identify features that predict delayed achievement of minimum clinically important difference (MCID) following elective lumbar spine fusion using Patient-Reported Outcomes Measurement Information System (PROMIS) surveys.

Summary Of Background Data: Preoperative prediction of delayed recovery following lumbar spine fusion surgery is challenging.

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Study Design: Retrospective analysis.

Objective: This study aimed to identify the prevalence of concomitant thoracic spinal and sternal fractures and factors associated with concomitant fractures.

Summary Of Background Data: The sternum has been implicated in stability of the upper thoracic spine, and both bony structures are included in the stable upper thoracic cage.

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Study Design: Retrospective study.

Objective: To evaluate outcomes and complications following operative and nonoperative management of hyperostotic spine fractures.

Methods: Patients presenting between 2008 and 2017 to a single level 1 trauma center with hyperostotic spine fractures had their information and fracture characteristics reviewed.

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Background: Infantile neuroaxonal dystrophy (INAD) is a rare, autosomal recessive disease due to defects in and is associated with lipid peroxidation. RT001 is a di-deuterated form of linoleic acid that protects lipids from oxidative damage.

Methods: We evaluated the pharmacokinetics (PK), safety, and effectiveness of RT001 in two subjects with INAD (subject 1: 34 months; subject 2: 10 months).

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Background Context: The prevalence of C2 fractures has increased in recent years. The treatment of these fractures include halo-vest immobilization (HVI), rigid cervical collar, or spinal fusion. There is controversy regarding the management of these fractures with different institutions having their own protocols based on individualized experience.

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Study Design: Retrospective database review.

Objectives: To determine factors associated with unplanned readmission, complications, and mortality in patients undergoing operative management for C2 fractures.

Methods: The American College of Surgeons-National Surgical Quality Improvement Program (ACS NSQIP) was queried between 2007 and 2014.

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Study Design: Retrospective.

Objectives: To evaluate complications and outcomes of halo immobilization in patients with cervical spine fractures treated at a level I trauma center.

Methods: A retrospective evaluation of patients treated at a single institution with halo immobilization from August 2000 to February 2016 was performed.

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Study Design: Case control series.

Objective: The aim of this study was to evaluate and compare the effectiveness of methods to decrease surgical site infections (SSIs) following spine tumor surgery.

Summary Of Background Data: With the aging population of the United States, the prevalence of cancer and associated metastatic spine disease is increasing.

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Study Design: Retrospective review of prospective data.

Objective: Determine whether patient reported outcome (PRO) data collected prior to lumbar discectomy predicts achievement of a minimal important difference (MID) after surgery. Compare ability of PRO and clinical information to predict achievement of MID in short term follow-up after discectomy.

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Background Context: Numerous studies have analyzed the impact of rheumatoid arthritis (RA) on the cervical spine and its related surgical interventions. However, there is a paucity of literature available conducting the same analyses in patients with non-cervical spine involvement.

Purpose: The objective of this study was to compare patient characteristics, comorbidities, and complications in patients with and without RA undergoing primary non-cervical spinal fusions.

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There is a paucity of literature describing the management of recurrent symptomatic postoperative epidural hematoma or uncontrollable intraoperative hemorrhage in posterior spine surgery. Traditional management with hematoma evacuation and wound closure over suction drains may not be effective in certain cases, and it can lead to recurrence and neurological injury. The authors report 3 cases of recurrent symptomatic postoperative epidural hematoma successfully managed with novel open-wound negative-pressure dressing therapy (NPDT), as well as 1 case of uncontrollable intraoperative hemorrhage that was primarily managed with the same technique.

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Study Design: Retrospective review.

Objectives: Large compressive pseudomeningocele causing a major neurologic deficit is a very rare complication that is not well described in the existing literature.

Methods: Institutional review board consent was obtained to study 2552 consecutive extradural spinal surgical cases performed by a single senior spinal surgeon during a 10-year period.

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Objective: To investigate risk factors and complications of cervical spine surgery in elderly patients.

Methods: A retrospective study was performed using data from the American College of Surgeons National Surgical Quality Improvement Program. Patients ≥65 years old who underwent cervical spine surgery from 2005 to 2013 were identified using International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis and Current Procedural Terminology codes.

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MINI: During the first half of the 20th century interest in spinal deformity grew due to common conditions of that era including polio and tuberculosis. This article will discuss Louis Arnold Goldstein, a visionary leader in spinal deformity surgery from Rochester, New York and one of the founders of the Scoliosis Research Society.During the first half of the 20th century interest in spinal deformity grew due to common conditions of that era including polio and tuberculosis.

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Background Context: There is a paucity of literature describing risk factors for adverse outcomes after geriatric lumbar spinal surgery. As the geriatric population increases, so does the number of lumbar spinal surgeries in this cohort.

Purpose: The purpose of the study was to determine how safe lumbar surgery is in elderly patients.

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Background: There is a paucity of literature describing the use of bone graft substitutes to achieve fusion in the pediatric spine. Outcomes and complications involving the off-label use of bone morphogenetic protein 2 (BMP-2) in the pediatric spine are not clearly defined. The purpose of this study is to review the existing literature with respect to reported outcomes and complications involving the use of low-dose BMP-2 in pediatric patients.

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