Publications by authors named "Robert M Feldman"
Objective: This study investigates the incidence and causes of diagnostic changes from primary open angle glaucoma suspect (POAGS) to primary open angle glaucoma (POAG), and vice versa, in clinical practice.
Design: This is a retrospective, single site, case-control study.
Participants: It includes patients over age 40 diagnosed with either POAG or POAGS between 2013-2020.
Compare postoperative outcomes in cataract surgery between eyes with standard drop regimen versus dropless protocol by residents. Retrospective cohort study between April 1, 2018 and March 31, 2020. The study was performed at Lyndon B.
View Article and Find Full Text PDFArticle Synopsis
- - The study compares the costs of two treatments for glaucoma: a second glaucoma drainage device (SGDD) and transscleral cyclophotocoagulation (CPC), finding CPC to be significantly cheaper for patients with inadequately controlled intraocular pressure.
- - In terms of total direct costs, the SGDD treatment averaged $8,790 compared to $4,090 for CPC, and similar trends were observed in costs during both the study and global periods (90 days).
- - The monthly costs after the initial treatment period were $215 for SGDD compared to $103 for CPC, with no significant difference in IOP-lowering medication costs between the two groups.
Purpose: To compare the intra-device repeatability and inter-device reproducibility between two anterior segment imaging instruments, the CASIA SS-1000 (Tomey Corp., Nagoya, Japan) and Pentacam (OCULUS, Arlington, WA) in measuring anterior segment parameters.
Methods: Single-center, prospective clinical trial.
Article Synopsis
- The study aimed to assess the safety and effectiveness of the Xen45 Gel stent compared to traditional glaucoma surgery options in patients with a history of failed surgical interventions.
- Results showed that the Xen group had a slightly lower failure rate and a significantly lower rate of serious complications compared to control treatments, though overall complication rates were similar between the two groups.
- After one year, there were no significant differences in intraocular pressure or medication use between the Xen and control groups, indicating comparable outcomes despite different surgical approaches.
Prcis: Short-term overall success rates were high with either SGDD or CPC. However, SGDD was associated with more clinic visits and an increased risk of additional glaucoma surgery. Both treatments were reasonable options for eyes with inadequately controlled IOP after a single GDD.
View Article and Find Full Text PDFPurpose: To determine risk factors that affect nonproliferative diabetic retinopathy (NPDR) progression and establish a predictive model to estimate the probability of and time to progression in NPDR. . Charts of diabetic patients who received an initial eye exam between 2010 and 2017 at our county hospital were included.
View Article and Find Full Text PDFPrecis: Lens extraction with endocycloplasty (LE/ECPL) results in greater angle deepening than LE alone in plateau iris eyes. This study directly compares an LE/ECPL treatment group with a control group.
Purpose: Quantitatively determine the effect of LE/ECPL versus LE alone for eyes with plateau iris configuration/plateau iris syndrome (PIC/PIS) on angle parameters.
Unlabelled: PRéCIS:: The potential parameters for differentiating pupillary block (PB) from plateau iris configuration (PIC) on anterior segment optical coherence tomography (ASOCT) are lens/pupil size parameters and angles. Further study is needed to determine a landmark peripheral to the centroid of the iris.
Purpose: Investigate anterior segment parameters to distinguish between 2 mechanisms of angle closure, PB and PIC, using swept-source Fourier domain ASOCT.
Background: Rising healthcare costs motivate continued cost-reduction efforts. To help lower costs associated with open-angle glaucoma (OAG), a prevalent, progressive disease with substantial direct and indirect costs, clinicians need to understand the cost-effectiveness of intraocular pressure (IOP)-lowering pharmacotherapies. There is little published information on clinicians' knowledge and attitudes about cost-effectiveness in glaucoma treatment.
View Article and Find Full Text PDFArticle Synopsis
- Primary open-angle glaucoma is more common and severe in people of African descent compared to those of European or Asian ancestry, yet they are often overlooked in genetic research on this condition.
- The study conducts a genome-wide association study (GWAS) involving nearly 10,000 participants from various countries to identify genetic links to the disease.
- Results suggest significant genetic variants associated with primary open-angle glaucoma, highlighting the need for more focused research on affected populations for better understanding and treatment options.
Purpose: To find genetic contributions to glaucoma in African Americans.
Design: Cross-sectional, case-control study.
Participants: One thousand eight hundred seventy-five primary open-angle glaucoma (POAG) patients and 1709 controls, self-identified as being of African descent (AD), from the African Descent and Glaucoma Evaluation Study (ADAGES) III and Wake Forest School of Medicine.
Purpose: To identify the presence or absence of 3 identifiable landmarks: trabecular meshwork (TM), Schlemm's canal (SC), and a novel landmark termed the band of extracanalicular limbal lamina (BELL), which is a landmark adjacent to SC visible on anterior segment (AS) OCT. These landmarks also were analyzed pathologically to identify all 3 landmarks.
Design: Retrospective review.
Purpose: Compare intraocular pressure (IOP) control and complication rates of a second glaucoma drainage device (GDD) to diode transscleral cyclophotocoagulation (TSCPC) following failure of an initial GDD.
Patients And Methods: Eyes with 1 GDD that required a second GDD or TSCPC for glaucoma control were included. Exclusion criteria were a cyclodestructive procedure before initial GDD, no light perception vision, or follow-up <1 year.
Purpose: To report long-term (>5 y) outcomes of plateau iris syndrome patients treated with argon laser peripheral iridoplasty (ALPI).
Patients And Methods: A retrospective chart review was performed on all patients with plateau iris syndrome treated with ALPI from 1996 to 2007. The study included 22 eyes from 22 patients with plateau iris after peripheral iridotomy that were followed for at least 1 year after ALPI.
Purpose: To assess the effect of examiner handedness on intraocular pressure (IOP) readings using the Tono-Pen XL in eyes without corneal pathology or previous ocular surgeries.
Patients And Methods: Patients 18 years of age or older were included in this prospective study. Participants who had a history of corneal conditions or other characteristics that would prevent reliable IOP measurements were excluded.
Objective: The objective was to evaluate the sensitivity and specificity of computed tomography (CT) diagnosis of open globes, determine which imaging factors are most predictive of open globe injuries, and evaluate the agreement between neuroradiologist and ophthalmologist readers for diagnosis of open and closed globes.
Methods: This study was a retrospective cohort study. Patients who presented to Memorial Hermann-Texas Medical Center with suspicion for open globes were reviewed.
. To evaluate interobserver, intervisit, and interinstrument agreements for gonioscopy and Fourier domain anterior segment optical coherence tomography (FD ASOCT) for classifying open and narrow angle eyes. .
View Article and Find Full Text PDFPurpose: To describe a new surgical technique to effectively close large (>180 degrees) cyclodialysis clefts.
Methods: Our method involves the use of procedures commonly associated with repair of retinal detachment and complex cataract extraction: phacoemulsification with placement of a capsular tension ring followed by pars plana vitrectomy and gas tamponade with light cryotherapy. We also used anterior segment optical coherence tomography (OCT) as a noninvasive mechanism to determine the extent of the clefts and compared those results with ultrasound biomicroscopy (UBM) and gonioscopy.
Purpose: To evaluate the changes in anterior chamber angle (ACA) parameters in primary angle closure (PAC) spectrum eyes before and after cataract extraction (CE) and compare to the changes after laser peripheral iridotomy (LPI) using anterior segment optical coherence tomography (ASOCT).
Methods: Twenty-eight PAC spectrum eyes of 18 participants who underwent CE and 34 PAC spectrum eyes of 21 participants who underwent LPI were included. ASOCT images with 3-dimensional mode angle analysis scans were taken with the CASIA SS-1000 (Tomey Corp.
Purpose: To determine and validate thresholds of anterior chamber angle (ACA) parameters in discriminating open- vs narrow-angle eyes using images from dedicated anterior segment optical coherence tomography (DASOCT).
Design: Reliability analysis.
Methods: Eyes imaged by DASOCT and examined with gonioscopy were reviewed.
Purpose: To evaluate the safety and efficacy of adding fixed-combination brinzolamide 1%/brimonidine 0.2% (BBFC) as adjunctive therapy to travoprost 0.004% (TRAV) in patients with open-angle glaucoma or ocular hypertension.
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