The effect of treatment on work productivity in patients with bladder cancer.

Objective: To describe the impact of bladder-preserving treatment vs. cystectomy on work productivity and activity impairment (WPAI) among patients with bladder cancer.

Methods: Using cross-sectional survey data, we constructed 2-part models involving both logistic and linear prediction to describe the relationship between WPAI and treatment modality among patients with non-muscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC).

Patient and Provider Perception of Transurethral Resection of Bladder Tumor vs Chemoablation for Nonmuscle-invasive Bladder Cancer Treatment.

Purpose: The aim of this mixed methods study was to investigate patient and provider perceptions of repeat transurethral resection of bladder tumors to improve counseling as new nonsurgical treatment modalities for nonmuscle-invasive bladder cancer emerge.

Materials And Methods: Quantitative data were collected via a web-based survey through the Bladder Cancer Advocacy Network of patients with nonmuscle-invasive bladder cancer who had undergone at least 1 transurethral resection of bladder tumor. Bivariable and multivariable analyses were performed to evaluate associations of patient demographics and clinical variables with treatment preference.

Minimal Patient-Reported Side Effects for a Chemoablative Gel (UGN-102) Used as Frontline Treatment in Adults with Nonmuscle-Invasive Bladder Cancer.

Purpose: Optima II ("OPTimized Instillation of Mitomycin for Bladder Cancer Treatment," clinicaltrials.gov: NCT03558503) was a phase 2b trial evaluating a nonsurgical alternative as a primary treatment for nonmuscle-invasive bladder cancer (NMIBC). Patients received 6 weekly instillations of UGN-102, a mitomycin-containing reverse thermal gel.

Quality of Life and Health State Utilities in Bladder Cancer.

Background: Bladder cancer treatments may variably impact health-related quality of life (QOL).

Objective: To characterize the quality of life of patients with bladder cancer at various time points across the continuum of bladder cancer care from non-muscle-invasive disease to metastatic bladder cancer and develop utility scores to inform cost-effective analyses.

Methods: We performed a cross-sectional survey of bladder cancer patients in the Bladder Cancer Advocacy Network Patient Survey Network.

Discomfort and relieving factors among patients with bladder cancer undergoing office-based cystoscopy.

Objective: To evaluate the degree of discomfort among patients with bladder cancer undergoing office-based cystoscopy and identify factors and interventions that influence discomfort and anxiety.

Methods: We conducted a survey of the Bladder Cancer Advocacy Network Patient Survey Network (BCAN PSN) to investigate the degree of discomfort associated with office-based cystoscopy and prevalence of interventions used to reduce discomfort. All patients had undergone at least one previous cystoscopy.

Testing Implementations of Geometric Dimensioning and Tolerancing in CAD Software.

Applying geometric and dimensional tolerances (GD&T) to part features in computer-aided design (CAD) software is essential so that the part will function properly and to guide downstream manufacturing and inspection processes. However, it is not well characterized how CAD software implements capabilities for a designer to apply GD&T to a part. Of course, CAD software vendors do their own internal testing of those capabilities and users evaluate CAD software so that it satisfies their CAD modeling requirements.

Patient empowerment through engagement in bladder cancer research.

Background: The Bladder Cancer Advocacy Network's (BCAN) Patient Survey Network established a diverse bladder cancer patient community who contribute to the prioritization of bladder cancer research topics through surveys and summits. This study describes our experience establishing an online learning program to train this population in research methods specific to bladder cancer and to subsequently engage patients in various stages of bladder cancer research.

Methods: We created online learning modules that addressed scientific concepts related to bladder cancer, creating the patient empowerment through engagement in research (PEER) program.

Microhematuria: AUA/SUFU Guideline.

Purpose: Patients presenting with microhematuria represent a heterogeneous population with a broad spectrum of risk for genitourinary malignancy. Recognizing that patient-specific characteristics modify the risk of underlying malignant etiologies, this guideline sought to provide a personalized diagnostic testing strategy.

Materials And Methods: The systematic review incorporated evidence published from January 2010 through February 2019, with an updated literature search to include studies published up to December 2019.

Reduction of Pain during Flexible Cystoscopy: A Systematic Review and Meta-Analysis.

Purpose: The BCAN (Bladder Cancer Advocacy Network) Patient Survey Network identified pain during intravesical procedures as a research priority for patients. Although intraurethral lidocaine is the standard of care in this setting, evidence of its use is equivocal. We systematically reviewed studies of interventions to reduce discomfort during cystoscopy and intravesical therapy of bladder cancer.

Automating robot planning using product and manufacturing information.

Advances in sensing, modeling, and control have made it possible to increase the accuracy of robots, and enable them to perform in dynamic environments. Often, performance deficiencies are not evident until late in the development of the manufacturing process, which delays the beginning of production and may cause damage to parts that have already undergone costly manufacturing steps. The goal of this research is to determine if a robot can meet manufacturing requirements, how to optimally plan robot activities, and to monitor robot processes to track performance.