Topo-Pachimetric Accelerated Epi-On Cross-Linking Compared to the Dresden Protocol Using Riboflavin with Vitamin E TPGS: Results of a 2-Year Randomized Study.

In the present study (clinical trial registration number: NCT05019768), we compared the clinical outcome of corneal cross-linking with either the standard Dresden (sCXL) or the accelerated custom-fast (aCFXL) ultraviolet A irradiation protocol using riboflavin-D-α-tocopheryl poly(ethylene glycol)-1000 succinate for progressive keratoconus. Fifty-four eyes of forty-one patients were randomized to either of the two CXL protocols and checked before treatment and at the 2-year follow-up. The sCXL group was subjected to CXL with 30 min of pre-soaking and 3 mW/cm UVA irradiation for 30 min.

Presbyopia treatment by monocular peripheral presbyLASIK.

Purpose: To investigate monocular peripheral presbyLASIK on the non-dominant eye with distance-directed monofocal refractive surgery on the dominant eye in treating presbyopia.

Methods: One hundred three patients underwent treatment with a VISX S4 system and follow-up from 1.1 to 3.